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Related to dedifferentiated: dedifferentiated liposarcoma
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Adj.1.dedifferentiated - having experienced or undergone dedifferentiation or the loss of specialization in form or function; "the hebephrenic--the most severely dedifferentiated of all schizophrenic patients"
undifferentiated, uniform - not differentiated
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References in periodicals archive ?
"Based on our knowledge and findings, this report is the first to report an extra-axial dedifferentiated brachyury-positive chordoma," they said.
Dedifferentiated Liposarcoma (DL) and (Pleomorphic Liposarcoma) PL were considered to be highly malignant, and had an incidence of 17.9% (7/39) and 5.1% (2/39) respectively.
Using this technique, they showed that human cells can also be dedifferentiated to an early embryonic stage.
Histological examination revealed a dedifferentiated liposarcoma of the cord with tumour-free margins of resection and no lymphovascular invasion.
Expanding the spectrum of malignant progression in solitary fibrous tumors: A study of 8 cases with a discrete anaplastic component--is this dedifferentiated SFT?
[sup][4] Liposarcomas were divided into the following five subtypes: well-differentiated liposarcoma, dedifferentiated liposarcoma, myxoid liposarcoma, pleomorphic liposarcoma, and mixed liposarcoma.
Dedifferentiated chondrocytes show decreased proteoglycan synthesis and type II collagen expression and increased type I collagen expression, thus failing to produce a mechanically normal cartilage extracellular matrix (ECM).
A tumor with this feature is often dedifferentiated EC, which comprises FIGO (Federation Internationale de Gynecologie et d'Obstetrique) grade 1 or 2 endometrioid carcinomas and undifferentiated carcinomas (19, 22).
Uterine LMS must be distinguished from other mesenchymal tumors, such as endometrial stromal sarcoma, adenosarcoma, carcinosarcoma, epithelial tumors, and dedifferentiated mixed tumors as the biology, patterns of recurrence, overall behaviors, and response to treatment are distinct from each other [8-10].
This is partly because these malignancies have lost the ability to take up radioactive iodine or have dedifferentiated to more aggressive types, making treatments ineffective [2].
Dedifferentiated liposarcoma of the small bowel mesentery presenting as a submucosal mass.
These formats have been described as "glocal," and all of them share scale disjunctions between the conditions of a particular locale and vast dedifferentiated global networks.