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Related to dedifferentiated: dedifferentiated liposarcoma
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Adj.1.dedifferentiated - having experienced or undergone dedifferentiation or the loss of specialization in form or function; "the hebephrenic--the most severely dedifferentiated of all schizophrenic patients"
undifferentiated, uniform - not differentiated
References in periodicals archive ?
Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells.
Chondroid chordomas are relatively less aggressive than conventional chordomas while the dedifferentiated chordomas are more aggressive, faster growing and more likely to metastasize.
5,6) These include cellular tumors with increased mitotic rates, atypical mitoses, or necrosis (Figure 14), and dedifferentiated tumors that show abrupt transition from low-grade MIFS to an undifferentiated pleomorphic sarcoma phenotype (Figure 15, A and B).
said Goodwin, who was diagnosed with dedifferentiated retroperitoneal liposarcoma, a soft-tissue cancer in his abdominal cavity.
Histologically, liposarcoma can be classified into five types, namely, mixed, myxoid, pleomorphic, dedifferentiated, and atypical lipomatous types.
However, dedifferentiated liposarcoma, low grade fibromyxoid sarcoma, deep benign fibrous histiocytoma, malignant peripheral nerve sheath tumour, (Sarcomatoid) mesothelioma, schwannoma, gastrointestinal stroma cell tumour, synovial sarcoma and leiomyoma were negative for STAT6.
To test their idea, they injected GABA inhibitors into undamaged zebrafish eyes and found that the fish developed a regenerative response: Muller glia in the retina dedifferentiated and proliferated.
Dedifferentiated liposarcoma of the lower extremity with low-grade dedifferentiation and low-grade osteosarcomatous component.
We describe an unusual case of rapidly growing foot dedifferentiated liposarcoma of foot which is rare.
Classification of liposarcoma has been described according to histological features, which establishes four subtypes: lipoma-like, myxoid differentiation, pleomorphic, and dedifferentiated liposarcoma.
Common types of liposarcoma include well-differentiated liposarcoma, myxoid, dedifferentiated, and pleomorphic liposarcoma.
Furthermore, as part of an additional analysis, patients with liposarcoma in Study 309 were categorized by three subtypes, dedifferentiated liposarcoma, myxoid/round liposarcoma and pleomorphic liposarcoma, and additional analyses were carried out on each subtype.