Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.
Reversion of a specialized cell or tissue to an unspecialized form. Dedifferentiation may occur before the regeneration of appendages in plants and certain animals and in the development of some cancers.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
(Biology) the reversion of the cells of differentiated tissue to a less specialized form
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
de•dif•fer•en•ti•a•tion(diˌdɪf əˌrɛn ʃiˈeɪ ʃən)
the loss of specialized form or condition previously acquired during development.
de`dif•fer•en′ti•ate`, v.i. -at•ed, -at•ing.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.