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Reversion of a specialized cell or tissue to an unspecialized form. Dedifferentiation may occur before the regeneration of appendages in plants and certain animals and in the development of some cancers.
(Biology) the reversion of the cells of differentiated tissue to a less specialized form
de•dif•fer•en•ti•a•tion(diˌdɪf əˌrɛn ʃiˈeɪ ʃən)
the loss of specialized form or condition previously acquired during development.
de`dif•fer•en′ti•ate`, v.i. -at•ed, -at•ing.