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n. Biology
Reversion of a specialized cell or tissue to an unspecialized form. Dedifferentiation may occur before the regeneration of appendages in plants and certain animals and in the development of some cancers.

de′dif·fer·en′ti·ate′ v.


vb (intr)
to undergo the process of dedifferentiation
ThesaurusAntonymsRelated WordsSynonymsLegend:
Verb1.dedifferentiate - lose specialization in form or function
develop - grow, progress, unfold, or evolve through a process of evolution, natural growth, differentiation, or a conducive environment; "A flower developed on the branch"; "The country developed into a mighty superpower"; "The embryo develops into a fetus"; "This situation has developed over a long time"
differentiate - become different during development; "cells differentiate"
References in periodicals archive ?
Dedifferentiated component exhibiting chondrosarcomatous dedifferentiation is very rare with only few cases reported in literature.
On the basis of these findings a diagnosis of dedifferentiated liposarcoma with chondosarcomatous dedifferentiation was made.
The phenomenon of dedifferentiation was first described by Dahlin and Beabout.