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Related to degeneration: macular degeneration


1. The process of degenerating.
2. The state of being degenerate.
3. Medicine Gradual deterioration of specific tissues, cells, or organs with corresponding impairment or loss of function, caused by injury, disease, or aging.
4. Biology The evolutionary decline or loss of a function, characteristic, or structure in an organism or species.
5. Electronics Loss of or gain in power in an amplifier caused by unintentional negative feedback.


1. the process of degenerating
2. the state of being degenerate
3. (Biology) biology the loss of specialization, function, or structure by organisms and their parts, as in the development of vestigial organs
4. (Biology)
a. impairment or loss of the function and structure of cells or tissues, as by disease or injury, often leading to death (necrosis) of the involved part
b. the resulting condition
5. (Electronics) electronics negative feedback of a signal


(dɪˌdʒɛn əˈreɪ ʃən)

1. the process of degenerating.
2. the condition or state of being degenerate.
[1475–85; < Late Latin]



go to hell in a handbasket To indulge in petty or sporadic dissipation; to carouse occasionally, in a small way; to degenerate bit by bit; gradually to go downhill morally. This slang expression is often used to describe typically adolescent anti-social behavior, usually of a temporary nature. However, it sometimes carries connotations of more serious and permanent moral decline. Its origin is unknown but it is interesting to speculate that it may be related to go to heaven in a wheelbarrow ‘to be damned’—handbasket replacing wheelbarrow to indicate the relative small-ness of one’s sins; hell replacing heaven to accommodate more literal minds. See go to heaven in a wheelbarrow, PUNISHMENT.

go to pot To deteriorate, to go downhill, to degenerate, to fall into a state of disuse or ruin. Although the exact origin of this expression is unknown, it may be related to the earlier phrase go to the pot, literally ‘to be cut into pieces like meat for the pot,’ and figuratively ‘to be ruined or destroyed.’

If it were to save the whole empire from going to pot, nobody would stay at home. (Pall Mall Gazette, February, 1884)

go to rack and ruin To degenerate, to deteriorate, to decline, to fall apart; also to go to rack and to go to ruin. Rack ‘destruction’ is a variant of wrack and wreck. The expression dates from at least 1599.

Everything would soon go to sixes and sevens, and rack and ruin. (Elizabeth Blower, George Bateman, 1782)

go to the dogs To degenerate morally or physically, to deteriorate, to go to ruin. The expression, which dates from at least the early 17th century, is thought to have come from the earlier Latin phrase addicere aliquem canibus ‘to bequeath him to dogs.’

Rugby and the school-house are going to the dogs. (Thomas Hughes, Tom Brown’s School Days, 1857)

on the high-road to Needham On the road to poverty or ruin; on the skids; suffering a mental, moral, or financial decline. This British expression, of infrequent occurrence, simply puns on need without reference to a specific locality.

on the skids On the road to poverty, ruin, disgrace, or oblivion; in a state of rapid deterioration or decline. The skids as denotative of a moral condition may derive from Skid Row. (See LOCALITY.) It appears frequently in longer phrases such as hit the skids ‘start on the downward path’ or put the skids under ‘cause the ruin or decline’ of a person or plan.

By 1929 Bix [Beiderbecke] was on the way down—not yet on the skids, but the good time and the big time was behind him. (Stephen Longstreet, The Real Jazz Old and New, 1956)

the seamy side The most disagreeable, unsavory, and offensive aspect; the sordid, perverse, degenerate, or immoral features. Literally, the seamy side refers to the wrong, or underside, of pieced fabric which shows the rough edges and seams of an otherwise acceptable article of clothing, tapestry, etc. The figurative use of the seamy side was pioneered by Shakespeare:

Oh fie upon them! Some such squire he was
That turned your wit the seamy side without,
And made you to suspect me with the Moor.
(Othello, IV, ii)

A commonly used derivative is seamy.

ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.degeneration - the process of declining from a higher to a lower level of effective power or vitality or essential quality
physical process, process - a sustained phenomenon or one marked by gradual changes through a series of states; "events now in process"; "the process of calcification begins later for boys than for girls"
attack - the onset of a corrosive or destructive process (as by a chemical agent); "the film was sensitive to attack by acids"; "open to attack by the elements"
obsolescence - the process of becoming obsolete; falling into disuse or becoming out of date; "a policy of planned obsolescence"
macular degeneration - eye disease caused by degeneration of the cells of the macula lutea and results in blurred vision; can cause blindness
2.degeneration - the state of being degenerate in mental or moral qualities
abasement, abjection, degradation - a low or downcast state; "each confession brought her into an attitude of abasement"- H.L.Menchken
3.degeneration - passing from a more complex to a simpler biological form
transformation, transmutation, shift - a qualitative change
abiotrophy - a loss of vitality and a degeneration of cells and tissues not due to any apparent injury
cataplasia - (biology) degenerative reversion of cells or tissue to a less differentiated or more primitive form


noun deterioration, decline, dissolution, descent, regression, dissipation, degeneracy, debasement the degeneration of our political system


Descent to a lower level or condition:


[dɪˌdʒenəˈreɪʃən] Ndegeneración f


[dɪˌdʒɛnəˈreɪʃən] n (physical, mental) [person] → dégénérescence f; [thing] → dégénérescence f


nDegeneration f; (of people, morals also)Entartung f


[dɪˌdʒɛnəˈreɪʃn] ndegenerazione f


n. degeneración, deteriorización gradual.


n degeneración f; age-related macular — degeneración macular senil
References in classic literature ?
Sickness speaketh in such craving, and invisible degeneration; of a sickly body, speaketh the larcenous craving of this selfishness.
I sip it with a delicious thrill of degeneration, as though I were Eve tasting the apple for the first time,--for "such a power hath white simplicity." Sin is for the innocent,--a truth which sinners will be the first to regret.
Drinking is one form of the many forms of degeneration that set in when white men are exposed too long to too much white light.
His face was described as bilaterally asymmetrical, and various other signs of degeneration were described.
Anne's imagination pictured forth so vividly the coming degeneration of her dear little house that it hurt her as severely as if it had already been an accomplished fact.
It is a pleasant thing to reflect upon, and furnishes a complete answer to those who contend for the gradual degeneration of the human species, that every baby born into the world is a finer one than the last.
There is no positive disease; there is only a chronic feebleness -- a fatty degeneration -- a want of vital power in the organ itself.
"I believe that you are suffering from what is called fatty degeneration of the heart, a disease which was first divined and explored by Laennec, the man who gave us the stethoscope, not so very many years ago.
And I'll say, 'Why, the funeral of that good-for-nothing, gambling, whiskey-drinking Burning Daylight--the man that died of fatty degeneration of the heart from sitting in night and day at the business game 'Yes ma'am,' I'll say, 'he's sure a gone 'coon, but I've come to take his place and make you happy.
The complete degeneration of the Revolution into anarchy and tyranny further served to plunge him into a chaos of moral bewilderment, from which he was gradually rescued partly by renewed communion with Nature and partly by the influence of his sister Dorothy, a woman of the most sensitive nature but of strong character and admirable good sense.
The too-perfect security of the Upper-worlders had led them to a slow movement of degeneration, to a general dwindling in size, strength, and intelligence.
His steps were the short and shuffling ones of a man advanced in years and in fatty degeneration, but of a sudden they stopped beneath my very eyes.