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v. de·grad·ed, de·grad·ing, de·grades
1. To lower in quality or value; make inferior or less valuable: land that was degraded by overgrazing; a virus that degrades the computer's performance.
2. To lower in dignity; dishonor or disgrace: seemed to feel that he was degrading himself in accepting the invitation. See Synonyms at debase.
3. To reduce in grade, rank, or status; demote.
4. Geology To lower or wear away by erosion or weathering.
5. To cause (an organic compound) to undergo degradation.
1. To fall to a lower rank or status.
2. To undergo degradation; decompose: a chemical that degrades rapidly.

[Middle English degraden, from Old French degrader, from Late Latin dēgradāre : Latin dē-, de- + Latin gradus, step; see ghredh- in Indo-European roots.]

de·grad′er n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.degrader - a person who lowers the quality or character or value (as by adding cheaper metal to coins)
individual, mortal, person, somebody, someone, soul - a human being; "there was too much for one person to do"
vulgariser, vulgarizer - someone who makes something vulgar
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
G1T48 is a potential best-in-class oral selective estrogen receptor degrader (SERD) for the treatment of ER+ breast cancer.
The Phase 1 clinical trial of ARV-471, an oral estrogen receptor-targeting PROTAC protein degrader, will evaluate the safety, tolerability, and pharmacokinetics of ARV-471 in patients with locally advanced or metastatic ER positive / HER2 negative breast cancer.
"Nous pouvons nous attendre a voir les inegalites augmenter entre les pays a revenu elevee et les pays a faible revenu et les conditions de travail se degrader pour les plus vulnerables, ainsi que des deplacements de population", a-t-elle averti.
In addition, to boost PROTAC research around the world, Boehringer Ingelheim has made the protein degrader compound MZ-1, developed at the University of Dundee, freely available through its opnMe portal in 2018.
Toutes les tentatives pour mettre fin a la guerre ont jusqu'ici echoue, et la situation humanitaire ne cesse de se degrader au Yemen, pays deja le plus pauvre de la peninsule arabique dont l'economie est en lambeaux.
MSX73 was predicted to the most potential degrader (Supplementary Table S3) to harbour six different catalytic domains.
Detoxification or removing of complex contaminant using microorganisms are the main approaches to oil spill bioremediation [8]; the growth and proliferation of oil degrader bacteria stimulated by adding growth-promoting substrates to the polluted sites (biostimulation) and inserting them to the contaminated locations (bioaugmentation) [7].
Music Break Thru Music Presents Battle For Warped Tour Round 3 with special guests Woe To The Conquered, Disowned, Degrader, Distinctions, Letting Go, Pinnacle, Premier, 11th Hour, 21st Century Fugitives, 6 p.m.
Ce groupe nous a laisse , et s'est dirige vers le mont Sammama sans nous agresser ni degrader nos vehicules ', a-t-il explique, signalant que ces derniers visaient les agents de securite qualifies de Tawaghits '.