The Company's lead program is in Phase 3, developing lonafarnib, a first-in-class prenylation inhibitor for the treatment of Hepatitis Delta Virus
M2 EQUITYBITES-June 6, 2019-Eiger BioPharmaceuticals names new vice president of Global Hepatitis Delta Virus
M2 PHARMA-June 6, 2019-Eiger BioPharmaceuticals names new vice president of Global Hepatitis Delta Virus
Net proceeds from the offering may be used by the company to fund activities in connection with its Hepatitis Delta Virus
(HDV) clinical programmes, advancing peginterferon lambda into a potentially registrational programme, supporting pipeline activities, and for working capital and general corporate purposes.
LIMT HDV enrolled a total of 33 patients with chronic Hepatitis Delta Virus
. Objectives of the study were to demonstrate comparable activity and improved tolerability of peginterferon lambda - Lambda - versus historical peginterferon alfa in HDV-infected patients.
Cirrhosis may appear either with a viral infection like hepatitis C virus, Delta virus
or hepatitis B virus (though this last one often leads to cancer without even developing cirrhosis), or for non-viral reasons as excessive alcohol drinking or related to non-alcoholic steatohepatitis2.
Risk of post-transfusion infection with the hepatitis delta virus
. A multicenter study.
Hepatitis delta virus
(HDV) causes the most aggressive form of viral hepatitis in humans, putting at least 20 million people worldwide at risk of developing liver fibrosis, cirrhosis, and liver cancer.
According to a literature search using PubMed, Embase, Scopus, Science Direct, Web of Science, and Google Scholar with the search terms "hepatitis delta virus
," "North Africa", and the names of the countries there is no systematic review or meta-analysis on the prevalence of HDV in this region which has been published in the 20 years between January 1, 1998, and December 31, 2017.
On the other hand, lifelong NAs and HBIG combination therapy should be administered to patients who are HBV DNA-positive at LT, those who are HBeAg positive, those with hepatitis delta virus
(HDV) or HIV coinfections, and those with HCC (810).
* High Prevalence of Hepatitis Delta Virus
among Persons Who Inject Drugs, Vietnam
Proceeds of the financing are intended for use to advance Eiger's diverse pipeline of clinical stage programs for the treatment of rare diseases, including the company's lead program for hepatitis delta virus
(HDV) infection, the most severe form of viral hepatitis.