denature

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de·na·ture

 (dē-nā′chər)
tr.v. de·na·tured, de·na·tur·ing, de·na·tures
1. To change the nature or natural qualities of.
2. To render unfit to eat or drink without destroying usefulness in other applications, especially to add methanol to (ethyl alcohol).
3. Biochemistry
a. To cause the tertiary structure of (a protein) to unfold, as with heat, alkali, or acid, so that some of its original properties, especially its biological activity, are diminished or eliminated.
b. To cause the paired strands of (double-stranded DNA) to separate into individual single strands.
4. Physics To add nonfissionable matter to (fissionable material) so as to prevent use in an atomic weapon.

de·na′tur·ant n.
de·na′tur·a′tion n.

denature

(diːˈneɪtʃə) ,

denaturize

or

denaturise

vb (tr)
1. to change the nature of
2. (Chemistry) to change (a protein) by chemical or physical means, such as the action of acid or heat, to cause loss of solubility, biological activity, etc
3. (Chemistry) to render (something, such as ethanol) unfit for consumption by adding nauseous substances
4. (Nuclear Physics) to render (fissile material) unfit for use in nuclear weapons by addition of an isotope
deˈnaturant n
deˌnaturˈation n

de•na•ture

(diˈneɪ tʃər)

v.t. -tured, -tur•ing.
1. to deprive (something) of its natural character, properties, etc.
2. to render (various alcohols) undrinkable by adding an unwholesome substance.
3. to treat (a protein or the like) by chemical or physical means so as to alter its original state.
[1675–85]
de•na′tur•ant, n.
de•na`tur•a′tion, n.

denature


Past participle: denatured
Gerund: denaturing

Imperative
denature
denature
Present
I denature
you denature
he/she/it denatures
we denature
you denature
they denature
Preterite
I denatured
you denatured
he/she/it denatured
we denatured
you denatured
they denatured
Present Continuous
I am denaturing
you are denaturing
he/she/it is denaturing
we are denaturing
you are denaturing
they are denaturing
Present Perfect
I have denatured
you have denatured
he/she/it has denatured
we have denatured
you have denatured
they have denatured
Past Continuous
I was denaturing
you were denaturing
he/she/it was denaturing
we were denaturing
you were denaturing
they were denaturing
Past Perfect
I had denatured
you had denatured
he/she/it had denatured
we had denatured
you had denatured
they had denatured
Future
I will denature
you will denature
he/she/it will denature
we will denature
you will denature
they will denature
Future Perfect
I will have denatured
you will have denatured
he/she/it will have denatured
we will have denatured
you will have denatured
they will have denatured
Future Continuous
I will be denaturing
you will be denaturing
he/she/it will be denaturing
we will be denaturing
you will be denaturing
they will be denaturing
Present Perfect Continuous
I have been denaturing
you have been denaturing
he/she/it has been denaturing
we have been denaturing
you have been denaturing
they have been denaturing
Future Perfect Continuous
I will have been denaturing
you will have been denaturing
he/she/it will have been denaturing
we will have been denaturing
you will have been denaturing
they will have been denaturing
Past Perfect Continuous
I had been denaturing
you had been denaturing
he/she/it had been denaturing
we had been denaturing
you had been denaturing
they had been denaturing
Conditional
I would denature
you would denature
he/she/it would denature
we would denature
you would denature
they would denature
Past Conditional
I would have denatured
you would have denatured
he/she/it would have denatured
we would have denatured
you would have denatured
they would have denatured
ThesaurusAntonymsRelated WordsSynonymsLegend:
Verb1.denature - add nonfissionable material to (fissionable material) so as to make unsuitable for use in an atomic bomb
alter, change, modify - cause to change; make different; cause a transformation; "The advent of the automobile may have altered the growth pattern of the city"; "The discussion has changed my thinking about the issue"
2.denature - modify (as a native protein) especially by heat, acid, alkali, or ultraviolet radiation so that all of the original properties are removed or diminished
alter, change, modify - cause to change; make different; cause a transformation; "The advent of the automobile may have altered the growth pattern of the city"; "The discussion has changed my thinking about the issue"
3.denature - make (alcohol) unfit for drinking without impairing usefulness for other purposes
alter, change, modify - cause to change; make different; cause a transformation; "The advent of the automobile may have altered the growth pattern of the city"; "The discussion has changed my thinking about the issue"
Translations

denature

vtdenaturieren; (= make unfit for eating, drinking also)ungenießbar machen
References in periodicals archive ?
This process is known as denaturation, and the denaturation of atelocollagen can be witnessed by particular rotation.
For the determination of thermal denaturation enzyme was incubated at 40-80AdegC for 15 min in an incubator with the same amount of phosphate buffer of pH 7.0 for controlled and 7.5 for stressed L.
This lot 1 includes: - the collection of conventional hazardous and non-hazardous waste (excluding chemical waste) from the valduc center, - the collection, transport and disposal of infectious health care waste (dasri) from the valduc center, - exploitation of the conventional waste collection area of the valduc center, - management of the means of collection and evacuation, - the transport, recovery and disposal of conventional waste, - exploitation of the inert waste storage areas of the valduc center, - the shredding of paper documents and digital media classified or not according to din 66399, - the denaturation of certain waste before evacuation, - management of internal and external traceability of all waste.
Previous studies usually focused on the frequency of PSE-like occurrence and evaluated the differences in the solubility of salt soluble proteins between normal and PSE-like meat to indicate the level of denaturation of PSE-like meat proteins [1,5].
For each primer (QnrA, QnrB, QnrC, QnrD, QnrS) amplification was executed as: single initial denaturation and bacterial lysis at 95AdegC for 10 minutes, followed by 35 cycles of denaturation at 95AdegC for 40 seconds, annealing temperature for QnrA, QnrB was 54AdegC, QnrC 50AdegC, QnrD 52AdegC, and QnrS 51AdegC, elongation at 72AdegC for 40 seconds followed by single final elongation at 72AdegC for 10 minutes.
This is made possible with the use of Epiprot 60 UL, a native milk protein concentrate produced directly from fresh milk through a cold filtration process allowing for minimal denaturation and optimal functional and nutritional properties.
The enzyme eliminates the requirement for expensive thermocyclers by not requiring the cyclical temperature changes or a high temperature denaturation step.
Our previous laboratory studies demonstrated subsurface thermal denaturation of tissues using near-infrared (IR) laser energy with applied cooling, to preserve 1-2 mm of the tissue surface [5-9].
This method measures the heat capacity change, associated with protein thermal denaturation, as a function of temperature.
The anti-inflammatory potential was evaluated by inhibition of albumin denaturation assay, membrane stabilization assay, and lipoxygenase enzyme inhibition assay, while antioxidant potential was evaluated through hydrogen peroxide scavenging assay and DPPH radical scavenging assay.
The denaturation of the protein is one problem caused by slow freezing with protein denaturation-dependent upon temperature [5].