The Supersentivty of
Denervated Structures: A Law of Denervation.
Evidence also suggests that the
denervated muscle, or muscle without function, is not normal and may be responsible for some of the metabolic problems related to SCI.
A number of miRNAs are differentially expressed and are highly involved in the pathophysiological process of
denervated muscles [13].
Recently, functional electrical stimulation (FES) of the paralyzed muscle, as a potential therapy for restoring function of a
denervated muscle system, has been debated as an innovative treatment in the management of patients with laryngeal paralysis [13, 14].
We suspected that, the rats have strong self-repair ability and quick recovering from cerebral infarction, although there was decrease in motor neurons due to transsynaptic degeneration in pathological studies at the later stage, the
denervated muscle fibers of those motor neuron may be reinnervated by the survived motor neurons, which may lead to the increase in CMAP amplitude and MUNE.
In all cases, the authors propose a relationship between increased MAP-2 expression and loss of afferents (deafferentation) of granule cells, as well as a redistribution of MAP-2 from innervated areas of the hippocampus to
denervated zones of the dentate gyrus.
Apomorphine is a DA receptor agonist that, at low doses, causes contralateral turning by stimulating both supersensitive D1 and D2 receptors, preferentially in the
denervated side.
The intact residual peripheral nerves are transferred to surgically
denervated areas of unused musculature in the residual limb or chest (Figure 1).
We resected, divided, and
denervated the stomach in a multitude of ways.
In this case the slope of heart rate change, during exercise, in
denervated animals was compared to the change seen in intact animals.
[sup][2] Following chorda tympani nerve damage, taste buds disappear from the
denervated side of the tongue [sup][3] and taste loss or distortion can occur.
It has been demonstrated that after a saphenous nerve injury, the sural nerve is able to send collateral axon sprouting to the
denervated saphenous area and this sprouting is 30 % larger in females (Kovacic et al, 2003).
