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Noun1.deoxyguanosine - a nucleoside component of DNA; composed of guanine and deoxyribose
nucleoside - a glycoside formed by partial hydrolysis of a nucleic acid
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Hepatitis B is a significant worldwide health problem, which is treated with entecavir, a common nucleoside (deoxyguanosine) analog with various side effects, such as lactic acidosis, myalgia, azotemia, hypophosphatemia, headache, diarrhea, pancreatitis, and neuropathy, and, in rare cases, cutaneous drug eruption (3,4,5).
Plasma levels of sCD40L, sP-selectin, 8-hydroxy-2-deoxyguanosine (8-OHdG), F1+2 were determined using commercial ELISA kits according to the manufacturers' instructions (human sCD40L ELISA, Bender Med, Austria; human sP-selectin ELISA, Bender Med, Austria; 8-hydroxy-2 deoxyguanosine ELISA, Northwest Life Science Specialties, LLC, USA; prothrombin F1+2 ELISA, Dade Behring Inc., USA).
Lech and coworkers [80] studied the influence of 8-O-methylguanine deoxyguanosine (Figure 6, 4) on GQ structures using the 24mer model TT(htel-21)A that forms a predominant hybrid-1 topology (Figure 2, 3) in [K.sup.+] solution [101].
The mixtures were subsequently applied to the HPLC-MS/MS system for the quantification of the two types of deoxyguanosine: dGuo and 8-oxodGuo.
MDA reacts with deoxyadenosine and deoxyguanosine in DNA, forming DNA MDA and other thiobarbituric acid reactive substances (TBARS) condense with two equivalents of thiobarbituric acid to give a fluorescent red derivative.
Formaldehyde-mediated modification of deoxyguanosine with amines: one-pot cyclization as a molecular model for genotoxicity.
Temporal variation of hydroxyl radical generation and 8-hydroxy-2'deoxyguanosine formation by coarse and fine particulate matter.
Entecavir, an oral drug of oral deoxyguanosine, was developed by Bristol-Myers Squibb and approved to enter the market by FDA in Mar.
Levels of the oxidative DNA damage marker, 8-hydroxyl-2- deoxyguanosine have been reported to be elevated in infertile men (61).
Increased oxidative DNA damage, as assessed by urinary 8-hydroxy-2'deoxyguanosine concentrations, and serum redox status in persons exposed to mercury.
ROS react with deoxyguanosine residues of DNA to form 8-dihydro-8-oxo-2'-deoxyguanosine (8-OxodG).