dephosphorylate


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dephosphorylate

(ˌdiːfɒsˈfɒrɪˌleɪt)
vb (tr)
to remove a phosphate group from (an organic compound)
References in periodicals archive ?
It binds to cyclophilin, its cytoplasmic receptor, and the CsA-cyclophilin complex binds to calcineurin, a serine-threonine phosphatase that is calcium- and calmodulin-dependent, inhibiting their ability to dephosphorylate nuclear factors present in the cytosol (2,3) as nuclear factor T cells (NF-ATc).
35] The present study revealed that MFN2 could influence cytoplasmic Ca 2+ levels, activating calcineurin to dephosphorylate NFAT in the nucleus.
Then the PCR products were treated with shrimp alkaline phosphatase (SAP) to dephosphorylate remaining dNTPs.
5 protein of herpes simplex virus 1 complexes with protein phosphatase 1 alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase.
Its efficacy to dephosphorylate the phytate in vitro has also been reported (Zyla et al.
For example, the brush border enzyme IAP can dephosphorylate LPS and reduce their toxicity (Koyama et al.
1] is also able to dephosphorylate a negatively regulating phosphorylation site in ZAP70 tyrosine-kinase (7).
These authors suggested that RCM enhance de novo ceramide synthesis and cause the activation of protein phosphatase 2A (PP2A) which in turn can dephosphorylate Akt.
Protein phosphatases (PP1 and PP2B) were able to dephosphorylate the PKC[alpha] phosphorylated N-DAT; however, none of the tested protein phosphatases dephosphorylated the ERK1 phosphorylated N-DAT.
Once the peptide reaches a critical density in stationery growth ph ase, it is sensed by VncS, which acts as a phosphatase to dephosphorylate the response regulator, VncR.
The "on" state lasts as long as the phosphatase that can dephosphorylate the enzyme is not present.
Tumor suppressor gene PTEN can dephosphorylate the second messenger phosphatidylinositol-3-phosphate (PIP3) to PIP2, antagonizing the activity of PI3K/Akt signal pathway.