A BECAUSE the patches come and go, it is unlikely you have vitiligo, as this causes permanent depigmentation
of the skin.
In a study of cryoepilation involving the eyelids in dogs and cats, 100% of the patients developed significant tissue swelling, edema, and skin depigmentation
. (11) The swelling and edema resolved in 8 days, and pigmentation to the eyelids returned within 6 months.
Be sure to follow up the patient for several weeks, because certain reactions such as depigmentation
take as long as 6 weeks.
Hypopigmentation or depigmentation
of the skin is very challenging to treat.
Other studies have found hypopigmentation and depigmentation
with this treatment.12
Mashiah and Brenner [sup] considered that imiquimod-induced depigmentation
was a cytotoxic T lymphocyte-mediated immune reaction, and Kim et al .[sup] thought that imiquimod could induce local apoptosis of human melanocytes, but the exact mechanisms was ambiguous.
Melgain lotion used for treatment of skin depigmentation
is acquired by Cadila Healthcare from Issar Pharma to make stronger its dermatological portfolio.
(11,12) Thus one can achieve a rapid repigmentation when it is used as a supplementary therapy along with grafting procedure.Clinical studies have shown that in case of split thickness skin grafting, supplemental NBUVB not only causes a rapid repigmentation, but also minimizes the chances of perigraft depigmentation
Alternatively surgical excision has been advocated because of the recognized complications including skin depigmentation
subcutaneous atrophy and recurrence following aspiration and corticosteroid injection.
There were no ocular complications such as limbus depigmentation
(Suguira sign) and no extraocular complications such as vitiligo, alopecia, poliosis, auditory dysfunction, and central nervous system damage findings during the 15 months follow-up period.
In his clinical experience, challenges and risks of performing aesthetic procedures on ethnic skin include postinflammatory hyperpigmentation and hypopigmentation, depigmentation
, keloids, and hypertrophic scars.
Vitiligo is a depigmentation
skin disorder caused by destruction of melanocytes.1 The prevalence of the disease is around 1% in the United States and Europe, while in rest of the world its ranges from less than 0.1% to greater than 8%.