Use of Cutaneous Depigmenting
Products by Women in Two Towns in Burkina Faso: Epidemiologic Data, Motivations, Products and Side Effects.
Topical steroid abuse: Its use as a depigmenting
When tested against other popular skin lighteners in a 4-week study, alpha-arbutin exhibited 20% and 60% higher depigmenting
activity than kojic acid and hydroquinone, respectively.
4 The proposed mechanism of action of glutathione for skin lightening is by direct inactivation of enzyme tyrosinase, mediating the switch from eumelanin to pheomelanin, quenching of free radicals and peroxidase and modulation of depigmenting
abilities of melanocytotoxic agents.
11,12) It is regularly used to treat aging skin, and as a depigmenting
Arbutin has diverse functions, including being an anti-oxidant and a depigmenting
They exhibited greater radical scavenging and melanin-inhibitory activity than the reference compounds ascorbic acid, BHT, alpha-tocopherol, arbutin and kojic acid proving its anti-oxidant and depigmenting
Hydroquinone, widely known as HQ, has been the "gold standard" in skin whitening for years and the most effective depigmenting
Arbutin: mechanism of its depigmenting
action in human melanocyte culture.
There are numerous modalities of treatment which are frequently used nowadays like sunscreens, topical depigmenting
agents (like hydroquinone, azelaic acid, kojic acid, retinoids, and corticosteroids), chemical peels (superficial, medium, and deep), laser therapy, cryotherapy, and dermabrasion [8, 9].
No effective treatment is available for LWNH though chemical peels 3, depigmenting
agents (16) and lasers have been tried without much success.
Vitiligo a depigmenting
disorder could account for psychological and social embarrassments.