In addition, patients may have erythroderma with desquamation
. "It's important to point out the difference between desquamation
, which is loss of the stratum corneum, and epidermal sloughing, which is what you see in something like [SJS] or TEN, where you're actually losing the entire epidermis," Dr.
The majority of the physical examination was normal; however, there was erythematous desquamation
around the umbilical stump and genitalia with no vesicles noted.
It is a member of serine protease inhibitor family.13 It has also been reported that vaspin is found in the hypothalamus and its levels can be detected in cerebrospinal fluid (CSF) in all healthy people.14 Besides, vaspin also has a protective effect against inflammation, obesity-related skin desquamation
and osteoporosis.15 Animal studies T2DM led to the discovery of vaspin in visceral adipose tissue and was directly related to obesity and IR.12 Vaspin levels increase with obesity, triglyceride (TG) levels, fasting insulin levels and IR.12 The correlation between how high or low vaspin levels are in relation to glucose and insulin levels could have potential future therapeutic and management roles.
Other findings included depigmented patches of itchy skin (Figure 1a, 1b), palmar desquamation
, weakness, hypotonia, and areflexia.
During recovery, desquamation
of the hands and feet occurs, with peeling of the skin beginning around the tips of the nails.
Acral erythema, (2) a symmetric, painful erythema of the palms and soles with a prodrome of paresthesia and occasional bullous formation with desquamation
upon resolution, is a rare side effect.
There is faint scale and superficial desquamation
between the skin folds.
Surprisingly, in the skeletal muscle the cystic structure surrounded by fibrous connective tissue (Figure 3g) and desquamation
of mucosa epithelium in the intestine was observed (Figure 3h).
Cheilitis simplex (chapped lips, common cheilitis, cheilitis sicca) is one of the most common subtypes, presenting as cracked lips, fissures or desquamation
of the lips, usually of the lower lip (Fig.
with erythema was also noted in the perianal area (Figure 2), and hence, Kawasaki disease (KD) was considered a strong clinical possibility.
Three findings, in particular eosinophilic microabscesses (MAB), superficial layering of eosinophils (SLE), and epithelial desquamation
(DE), are noteworthy.