deuteration


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deu·ter·ate

 (do͞o′tə-rāt′, dyo͞o′-)
tr.v. deu·ter·at·ed, deu·ter·at·ing, deu·ter·ates
To introduce deuterium into (a chemical compound).


deu′te·ra′tion n.

deuteration

(ˌdjuːtəˈreɪʃən)
n
the process of introducing deuterium into a molecule or chemical compound
References in periodicals archive ?
System-dependent effects of specific deuteration with aldehyde oxidase cleared drugs," Drug Metabolism and Disposition, vol.
Effect of W-methyl deuteration on metabolism and pharmacokinetics of enzalutamide.
At first, aromatic ring protons of Tyr and His residues (twelve each) were used for monitoring the conformational change of the T[F.sub.1][beta] monomer on nucleotide binding in solution, because of their relatively sharp NMR signals on deuteration of the other ring protons.
Noirault et al., "Isotopic effect study of propofol deuteration on the metabolism, activity, and toxicity of the anesthetic," Journal of Medicinal Chemistry, vol.
The intensity of molecular ion in the mass spectra of porphyrin has also been used in the study of deuteration (as a general example of electrophilic substitution) of porphyrins, metalloporphyrins, and some reduced derivatives.
Selective deuteration of the methyl groups gave insight into the packing of the micelle core (1).
The lower intensities of the bands close to 1582 and 1565 [cm.sup.-1] observed at [p.sup.2]H 4.0 may be ascribed to deuteration, at least partial, of ionized carboxyl group of aspartic and glutamic acid (Barth 2000).
(34) Deuteration of chloroform to deuterochloroform (CD[Cl.sub.3]) decreases its metabolic rate, thereby reducing liver and lung toxicity in rats by five to seventy percent over chloroform.
Subpicosecond spectroscopy of liquid water in the infrared: Effect of deuteration on the structural and vibrational dynamics.