The study, also known as ABT-001, is intended for patients 6 months to 2 years of age, or patients older than 2 years with a cognitive Developmental Quotient
of 60% or above.
The general developmental quotient
(DQ) is the average of the four subquotients.
If at age 2 he achieved one-year milestones, he would have a developmental quotient
of 50 (1/2 x 100).
Using the scale, a Developmental Age (DE) and Developmental Quotient
(DQ) were obtained for each area, as well as a total score combining all areas.
And 22 children who had developmental delay (12 with language delay and 10 with global developmental delay) were matched with the autism group based on chronological age, verbal and nonverbal developmental quotient
as assessed on the Mullen Scales of Early Learning, and overall functioning.
To overcome this methodological difficulty, almost all developmental tests compute the developmental quotient
(DQ = developmental age divided by chronological age x 100) as a relative measure.
Normative data were gathered from 2008 children drawn from an ethnically and socioeconomically heterogeneous population, with 81% of children judged "at-risk." (28) The items were picked to represent the developmental quotient
(DQ) of 75 to 100.
A more recent study involved 114 low birthweight infants at age 2 years; 27% of the children with severe IVH (grades III, IV) developed severe disabilities. The Griffiths' Mental Developmental Scale was used to evaluate cognitive status, where developmental quotient
over 85 is considered normal.
The results illustrate that infants who were placed in child care had an inferior developmental quotient
compared to those who did not have such experience.
The total developmental quotient
was also higher than that of the total group (DQ = 81 versus DQ = 60).
The age equivalents were used to estimate both subquotients and a general developmental quotient
The final outcome in the cases at 4th visit was the mean motor developmental quotient
of 79.43 with standard deviation of 9.85 compared to controls who had mean motor developmental quotient
of 88.00 with standard deviation of 4.50.