BeiGene (BGNE) announced that Revlimid has been approved by the China Food and Drug Administration, or CFDA for the treatment of multiple myeloma in combination with dexamethasone
in adult patients with previously untreated MM who are not eligible for transplant.
Mustafa Iqbal has successfully implanted dexamethasone
implants in Khyber Pakhtunkhwa.
Thousand Oaks, California-based human therapeutics developer Amgen (NASDAQ: AMGN) has received a positive opinion from Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency recommending a label variation for Kyprolis (carfilzomib) to include updated overall survival data from the Phase 3 head-to-head ENDEAVOR trial in patients with relapsed or refractory multiple myeloma (Kyprolis and dexamethasone
[Kd] versus Velcade [bortezomib] and dexamethasone
[Vd]), the company said.
The CHMP has chosen a positive opinion recommending a label variation for the product to include updated overall survival data from the Phase three head-to-head ENDEAVOR trial in patients with relapsed or refractory multiple myeloma (KYPROLIS and dexamethasone
compared with Velcade [bortezomib] and dexamethasone
DARZALEX is indicated in Europe for use in combination with lenalidomide and dexamethasone
, or bortezomib and dexamethasone
, for the treatment of adult patients with multiple myeloma who have received at least one prior therapy and as monotherapy for the treatment of adult patients with relapsed and refractory multiple myeloma, whose prior therapy included a PI and an immunomodulatory agent and who have demonstrated disease progression on the last therapy.
Moreover, prophylactic dexamethasone
has been shown to be effective in reducing the incidence of laryngeal oedema and postoperative nausea & vomiting.
The study focused on the effects of Cymerus MSCs in combination with or in comparison to the corticosteroid dexamethasone
, commonly used to treat exacerbations of asthma in human patients.
CheckMate-602: An Open-Label, Randomized Phase 3 Trial of Combinations of Nivolumab, Elotuzumab, Pomalidomide and Dexamethasone
in Relapsed and Refractory Multiple Myeloma
The study was designed to determine the effectiveness of single pre-operative submucosal injection of dexamethasone
in reducing post operative swelling and trismus after surgical removal of impacted mandibular molar when compared with control.
Group A comprised controls, Group B animals were administered dexamethasone
4mg/kg body weight per day intra-peritoneally, and Group C animals were given magnesium sulphate 20mg/kg body weight per day intramuscularly, with dexamethasone
at same dose as in Group B.
lonizable material in solution such as dexamethasone
sodium phosphate will migrate toward the poles of opposite charge superimposed on this migration.
1] of a recent trial of single-dose dexamethasone
for acute asthma compared with the current standard of 5-day prednisone.