diabetes insipidus

Also found in: Thesaurus, Medical, Acronyms, Encyclopedia, Wikipedia.
Related to diabetes insipidus: nephrogenic diabetes insipidus, diabetes mellitus, SIADH

diabetes in·sip·i·dus

A chronic disorder marked by excessive urination and usually intense thirst and dehydration, caused either by insufficient production or release of the pituitary hormone vasopressin or by inability of the kidneys to respond effectively to vasopressin.

[New Latin diabētēs īnsipidus, literally, insipid diabetes (so called because the urine of those suffering from the disease lacks the sweet taste characteristic of diabetes mellitus) : Medieval Latin diabētēs, diabetes; see diabetes + Latin īnsipidus, insipid; see insipid.]

diabetes insipidus

(Pathology) a disorder of the pituitary gland causing excessive thirst and excretion of large quantities of dilute urine
[C18: New Latin, literally: insipid diabetes]

diabe′tes in•sip′i•dus

(ɪnˈsɪp ɪ dəs)
a disorder characterized by increased urine production caused by inadequate secretion of vasopressin by the pituitary gland.
[< New Latin: literally, bland diabetes]

diabetes insipidus

A condition in which, usually, the pituitary in the brain is faulty and the kidneys do not absorb enough water, resulting in a high urine output and intense thirst.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.diabetes insipidus - a rare form of diabetes resulting from a deficiency of vasopressin (the pituitary hormone that regulates the kidneys); characterized by the chronic excretion of large amounts of pale dilute urine which results in dehydration and extreme thirst
diabetes - a polygenic disease characterized by abnormally high glucose levels in the blood; any of several metabolic disorders marked by excessive urination and persistent thirst
nephrogenic diabetes insipidus - diabetes insipidus caused by a failure of the kidney to respond to normal levels of vasopressin

di·a·be·tes in·sip·i·dus

n. diabetes insípida nefrógena, causada por una deficiencia en el gasto de hormona antidiurética.
References in periodicals archive ?
The patient was diagnosed with central diabetes insipidus. Pituitary profile was in a reasonable limit, except for prolactin, which was 32 ng/dL that was slightly higher than the upper limit.
The commonest pituitary lesion was Prolactinoma in 26 (26.8%) patients, followed by Sheehan's syndrome in 13 (13.4%) patients, Acromegaly in 12 (12.4%), non-secretory pituitary adenoma in 12 (12.3%), Hypogonadotropic hypogonadism in 10 (10.3%) and Craniopharyngioma in 7 (7.2%) patients, while miscellaneous disorders including Pan hypopituitarism, Cushing's disease, Empty sella syndrome, Ectopic Cushing's, Diabetes Insipidus, Autoimmune hypophysitis, TSHoma and Suprasellar mass etc.
After being allowed home for the second time, Conner seemed to be back to his old self, but he was suffering with major health conditions such as hormone deficiency, diabetes insipidus, total loss of sight in his right eye and partial remaining sight in his left eye.
Desmopressin acetate (0.1 [micro]g/kg/day, melt form) treatment was started for diabetes insipidus (DI).
Diabetes insipidus is characterized by an impaired renal water reabsorption, leading to polyuria and consequently, polydipsia (Kortenoeven & Fenton).
Oscar also developed diabetes insipidus, a rare life-long disorder which means his body cannot retain enough water.
Persistent nephrogenic diabetes insipidus, hyperparathyroidism and hypothyroidism after lithium treatment.
Juvenile diabetes mellitus, optic atrophy, hearing loss, diabetes insipidus, atonia of the urinary tract and bladder, and other abnormalities (Wolfram syndrome).
The initial treatment of prolactin-secreting adenomas was dopaminergic agonists, rather than neurosurgery.[6] Adrenocorticotropic hormone-secreting adenomas accounted for approximately 12.28% of all pituitary adenomas in the CPDRN, which is higher than the 1-7% reported in Finland; this outcome is related to PUMCH's expertise in Cushing's disease, which affects patients' choice of hospital.[6] Craniopharyngioma (95, 0.66%), Rathke's clef cysts (74, 0.51%), hypophysitis (6, 0.04%), germinoma (3, 0.02%), pituitary carcinoma (44, 0.31%), and diabetes insipidus (1, 0.01%) were in the minority diagnoses, while no cases of histiocytosis have been entered in the registry [Table 1].{Table 1}
During the preoperative period, it is misdiagnosed as pituitary adenoma in up to 40% of cases (2), although these two clinical entities can be readily distinguished based on the absence of diabetes insipidus in patients with adenoma (1).
It is characterized by normolipemic disseminated xanthomatosis that tends to localize on the face, trunk, flexural and intertriginous surfaces, is often associated with diabetes insipidus, and appears to run a chronic benign course.1 The disease predominantly affects male children and young adults.
The company is already invested in desmo-pressin acetate, a peptide-based drug that can treat diabetes insipidus, as well as certain bleeding disorders and bed-wetting problems.

Full browser ?