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Related to diagnostic specificity: diagnostic sensitivity


a. Explicitly set forth; definite: wrote specific instructions. See Synonyms at explicit.
b. Clear or detailed in communicating: Be specific when telling us what you need.
a. Limited, distinctive, or unique: problems specific to small colleges.
b. Intended for, applying to, or acting on a particular thing: a specific remedy for warts.
c. Concerned particularly with the subject specified. Often used in combination: "age-specific voting patterns" (A. Dianne Schmidley).
3. Relating to, characterizing, or distinguishing a species: a specific name.
a. Designating a disease produced by a particular microorganism or condition.
b. Having a remedial influence or effect on a particular disease.
5. Immunology Having an affinity limited to a particular antibody or antigen.
a. Designating a customs charge levied on merchandise by unit or weight rather than according to value.
b. Designating a commodity rate applicable to the transportation of a single commodity between named points.
a. Something particularly fitted to a use or purpose.
b. A remedy intended for a particular ailment or disorder.
a. A distinguishing quality or attribute.
b. specifics Distinct items or details; particulars.

[Medieval Latin specificus : Latin speciēs, kind, species; see species + Latin -ficus, -fic.]

spe·cif′i·cal·ly adv.
spec′i·fic′i·ty (spĕs′ə-fĭs′ĭ-tē) n.


(ˌspɛs əˈfɪs ɪ ti)

1. the quality or state of being specific.
2. Biol. the selective attachment or influence of one substance on another, as of an antibiotic on its target organism.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.specificity - the quality of being specific rather than general; "add a desirable note of specificity to the discussion"; "the specificity of the symptoms of the disease"
particularity, specialness - the quality of being particular and pertaining to a specific case or instance; "the particularity of human situations"
2.specificity - the quality of being specific to a particular organism; "host specificity of a parasite"
particularity, specialness - the quality of being particular and pertaining to a specific case or instance; "the particularity of human situations"
References in periodicals archive ?
In one study the abundance of 813 proteins in plasma was measured with a new aptamer-based proteomic technology, leading to the identification of potential biomarkers that discriminated cases from controls with 91% diagnostic sensitivity and 84% diagnostic specificity in cross-validated training and 89% diagnostic sensitivity and 83% diagnostic specificity in a separate verification set, with similar performance for early and late-stage non-small cell lung cancer (32).
Ward: In RA, ACPAs have a higher diagnostic specificity compared with rheumatoid factor and also have prognostic importance.
When evaluated against OF collected with the Intercept[R] device with a 0.5-[micro]g/L LCMS/MS THC limit of quantification (LOQ), the earlier version of the DrugTest 5000 device had 49.5% diagnostic sensitivity, 100% diagnostic specificity, and 55% efficiency (6).
Therefore, although the diagnostic sensitivity of these NEN markers is low at these higher cutoffs (CgA-IR, 20% at 500 pmol/L; CART-IR, 17%at 500 pmol/L; CgB-IR, 12% at 250 pmol/L), the diagnostic specificity for NEN diagnosis is very high (100% for all 3 bio markers).
We calculated the positive percent agreement (diagnostic sensitivity) by dividing the detected positives by the known clinically positive samples and multiplying by 100, and the negative percent agreement (diagnostic specificity) by dividing the detected negatives by the known healthy controls and multiplying by 100.
Percentages for samples from individuals exceeding the various cutoffs, diagnostic sensitivity, diagnostic specificity, positive predictive value, and negative predictive value (with 95% CIs) were calculated for the combined serious outcome (death, MI, heart failure, serious arrhythmia, refractory ischemic cardiac pain).
John Blackwood: The challenge is to demonstrate an adequate level of diagnostic specificity at the 99th-percentile upper reference limit.
This evolution has led to a decrease in diagnostic specificity for the diagnosis of AMI, a concern to many clinicians who may incorrectly equate any increased cardiac troponin value to an AMI (7, 8).
SDI improves diagnostic specificity by dramatically reducing excision of benign pigmented lesions: in one large Belgian study, by up to 75% (Br J Dermatol.
Reflectance-mode confocal microscopy of pigmented skin lesions-improvement in melanoma diagnostic specificity. J Am Acad Dermatol.
We therefore emphasized the diagnostic specificity of the SD-OCT parameters, which were well in distinguishing between normal and POAG in previous studies.

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