Identification of b-glucuronidase-resistant diastereomeric
glucuronides of 3-hydroxy-3methyloxindole formed during 3-methylindole metabolism in goats.
The result of the calculation is called the diastereomeric
factor (DF) or the enantiomeric factor (EF) .
The phosphorus atom from CHP diester end groups gives two distinct singlets with very close chemical shifts because of the presence of more than one diastereomeric
species in the molecules of the products.
Chmutova et al., "Conformational isomerism in 3,5,8-trioxabicyclo [5.1.0]octane and its diastereomeric
It has however been reported that coordination compounds form diastereomeric
complexes via intimate ion-pair formation [79-81].
Furthermore, trans-2-hexadecenal reacts readily with deoxyguanosine and DNA to produce the diastereomeric
cyclic 1,N(2)-deoxyguanosine adducts 3-(2-deoxy-[beta]-d-erythro-pentofuranosyl)-5,6,7,8-tetrahydro-8R-hydroxy-6R-tridecylpyrimido[1,2-a]purine-10(3H)one and 3-(2-deoxy-[beta]-d-erythro-pentofuranosyl)-5,6,7,8-tetrahydro8S-hydroxy-6S-tridecylpyrimido[1,2-a]purine-10(3H)one .
Briefly, LGM2605 was synthesized from vanillin via secoisolariciresinol and a glucosyl donor (perbenzoyl-protected trichloroacetimidate under the influence of TMSOTf) through a concise route that involved chromatographic separation of diastereomeric
My Master's thesis (Potassium Triphenylmethide: A Strong Base for Organic Synthesis) and PhD dissertation (Conformational Studies of Diastereomeric
Sets of tert-Butyl Octalones using Proton and Carbon-13 NMR Spectroscopy) provided me with opportunities to expand my knowledge of laboratory techniques (e.g.
association complex between the substrate and
Investigation of the enzymatic cleavage of diastereomeric
oligo3-hydroxybutanoates containing two to eight HB subunits.
2002) and using the chemical shift difference of the diastereomeric
protons at C-26 (Agrawal 2005) revealed that compound 1 was a 7:3 mixture of the 25R and 25S epimers.
Indeed, the two terminal methyl groups of the diastereomeric
MaNP ester (R,R)- and (R,S)-13, derived from [epsilon]-chiral alcohol (R)-11, showed completely separate [sup.1]H NMR signals, while the diastereomeric
MTPA ester 12 showed no separation (Scheme 14).