Procaine, mepivacaine, lidocaine, ropivacaine, oxybuprocaine, tetracaine, bupivacaine, T-caine and dibucaine
are local anesthetics that were reported  to be simultaneously detected by a high-performance liquid chromatography-tandem mass spectrometry method.
 Local dibucaine
Immediately (2009) injection Liu et al.
BuChE activity and phenotypes were determined using benzoylcholine chloride (50 [micro]mol/l) as substrate in the presence or absence of dibucaine
hydrochloride (10 [micro]mol/l) and sodium fluoride (50 [micro]mol/l) as inhibitor of enzyme described previously (25).
was synthesized and used by Jones in 1930.
In order to assess the patient's pseudocholinesterase enzyme quantity and function, blood was sent for laboratory analysis of enzyme level and dibucaine
Nupercainal is a rectal anesthetic that utilizes 1% dibucaine
to temporarily relieve the pain and itching of hemorrhoids and other problems in the rectal area.
Organic ammonium salts with local anaesthetic activity (e.g., dibucaine
and tetracaine, which exhibit properties of protonophores) lower the proton gradient between the inside and the outside of the thylakoid membrane, causing loss of ability to form ATP .
The amide group of local anaesthetic agents include: bupivacaine, L-bupivacaine, lidocaine, ropivacaine, prilocaine, dibucaine
, etidocaine and mepivacaine.
The test quantifies BChE enzyme activity in the serum in the presence and absence of the competitive inhibitor dibucaine
, allowing the calculation of a "dibucaine
number" (DN) that corresponds to the percentage of enzymatic inhibition: DN = [1--(Inhibited BChE activity)/(Total BChE activity)] X 100, where BChE activity is in units per liter.
Local anesthetics are given by injection or topically, and include benzocaine, bupivacaine (Marcaine, Sensorcaine), chloroprocaine (Nesacaine), camphor, dibucaine
(Nuper-cainal), levobupivacaine (Chirocaine), lidocaine (Xylocaine, Octocaine), mepivacaine (Carbocaine, Polocaine), pramoxine, prilocaine (Citanest), procaine (Novocaine), ropivacaine (Naropin), and tetracaine (Pontocaine).