We have seen this for CVS vs amnio cytogenetics, diethylstilbesterol
cancer risks, choroid plexus cysts, intracardiac echogenic focus, and numerous others ultrasound markers.
Worsening of the disease with pregnancy, oral contraceptive use, in postmenopausal women on combination of estrogen and progesterone for osteoporosis, male patients receiving diethylstilbesterol
for prostate cancer, (5,6) points to hormonal etiology of melasma.
Hsp90 and environmental impacts on epigenetic states: a model for the trans-generational effects of diethylstilbesterol
on uterine development and cancer.
A dose dependent increasing trend was observed for gnestein supplemented birds.Isoflavones have a common diphenolicstructure that resembles the potent synthetic estrogen diethylstilbesterol
and hexestrol (Tham et al., 1998).
Phytoestrogens are natural phytochemicals, which are found in plants and their products, and are structurally and functionally similar to oestradiol-17b (isoflavone) or synthetic estrogens such as diethylstilbesterol
Available hospital services, marital status, parity, history of preterm birth, in utero exposure to diethylstilbesterol
, in vivo fertilization for index pregnancy, pregnancy complications such as gestational and pre-existing diabetes mellitus, antepartum bleeding and anemia, maternal weight gain, smoking, illegal drug use, uterine distension (e.g., polyhydramnios, multifetal pregnancy) are other factors associated with PPROM.
BPA is often described as a weak estrogen because the dose needed to stimulate breast-cancer cell growth is 100,000 times higher than estradiol, the main estrogen receptor found on breast cancer cells.4 However, BPA has been shown to alter cell function and prolactin secretion at very low doses, less than 1 part per trillion.4 Despite BPA's having lower estrogenicity than estradiol, in in vivo studies its estrogenicity is only 100-fold lower than that of diethylstilbesterol