dipeptidase


Also found in: Medical, Encyclopedia, Wikipedia.

di·pep·ti·dase

 (dī-pĕp′tĭ-dās′, -dāz′)
n.
An enzyme that catalyzes the hydrolysis of dipeptides into their constituent amino acids.

dipeptidase

(daɪˈpɛptɪˌdeɪs)
n
an enzyme secreted in the small intestine that hydrolyzes dipeptides, splitting each into two separate amino acids before absorption
References in periodicals archive ?
poeyi, and therefore the purpose of this study could contribute in the determination of the expression changes in trypsin (TRY), bile salt-dependent lipase (BAL), a-amylase (AMY) and nonspecific cytosolic dipeptidase (CNP) during C.
The enzymes are dehydrogenase that reduces pyruvate into D-Lactate, ligase that synthesizes D-Alanyl-D-Lactate and a dipeptidase that hydrolyzes D-Alanyl-D-Alanine.
Because ACE inhibitors are nonspecific carboxyl dipeptidase inhibitors that affect a number of proteases, it is possible that mechanisms involving other proteases are influencing the drinking behavior and blood pressure (Takei & Tsuchida 2000).
ACE is a peptidyl dipeptidase A and primarily cleaves a decapeptide (angiotensin-I) to an octapeptide (angiotensin-II) which is a potent vasoconstrictor.
explored such possibility by analyzing circulating miRNAs in plasma of T2D patients before and after dipeptil dipeptidase IV inhibitor (DPP-IVi) sitagliptin therapy.
MCTR1 is the proposed precursor to MCTR2 and MCTR3, and gamma-glutamyltransferase (GGT) converts MCTR1 to MCTR2, which is then converted to MCTR3 by a dipeptidase (DPEP) enzyme (Figure 1).
(40) Other tumor-suppressor genes located on chromosome 16 that have shown loss of expression in LCIS include the CCCTC-binding factor (CTCF) gene, a transcriptional regulator of several genes linked to tumorigenesis, as well as the dipeptidase 1 (DPEP1) gene, which is involved in the metabolism of an important glutathione that may have a role in the degradation of the surrounding extracellular matrix.
The localization of the gene on chromosome 18q22.3-23 was the first identified genetic loci in Turkish DKD patients of T2DM [4], which is in the region of carnosinase genes, and the polymorphism of relevant genes of carnosine dipeptidase (CNDP)1 and 2 was later proved to be related with the progression of DKD in T2DM patients [5,6].
Cysteinylglycine was then taken up into cytoplasm and cleaved into cysteine and glycine by aminopeptidases A, B, and N and dipeptidase D, which could be utilized as a source of cysteine and glycine.
Identification and characterization of a mouse dipeptidase that hydrolyzes L-carnosine.
Genes involved protein (n = 104: e.g., dipeptidase 1, 26S protease regulatory subunit 6A, matrix metalloproteinase-17); nucleic acid (n = 91: e.g., ribonuclease T2, DNA helicase INO80); carbohydrate (n = 44: e.g., lactate dehydrogenase, pyruvate dehydrogenase, citrate synthase, succinate dehydrogenase, isocitrate dehydrogenase); lipid (n = 30; e.g., elongation of very long chain fatty acids protein 6, long-chain-fatty-acid-CoA ligase 1); and amino acid (n = 25: e.g., L-asparaginase, cysteine dioxygenase type 1, cysteine/glutamate transporter) metabolism were all differentially expressed in large numbers.