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Variant of bisphosphonate.
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Technetium-99m-methylene diphosphonate bone scintigraphy also confirmed a single abnormal fixation at L3-L4 level, and transthoracic echocardiography revealed no valvular lesion or abscess.
Bone scintigraphy with (99m)technetium-hydroxymethylene diphosphonate allows early diagnosis of cardiac involvement in patients with transthyretin-derived systemic amyloidosis.
Bone scan--A triple phase bone scan using methylene diphosphonate consists of a flow phase, a blood pool phase ten minutes after injection, and a delayed update phase that is performed three hours after injection.
It uses technetium-99 along with methylene diphosphonate as phosphated radiotracer which is absorbed by hydroxyapatite crystals and calcium (24) (figure 4).
99m] Tc-Methylene Diphosphonate (MDP) bone scan was performed.
Amstutz, "Results of the administration of diphosphonate for the prevention of heterotopic ossification after total hip arthroplasty," The Journal of Bone & Joint Surgery--American Volume, vol.
Currently, drugs for the prevention and treatment of osteoporosis are mainly categorized into bone resorption inhibitor which includes diphosphonate (alendronate, etidronate and risedronate), sex hormone, calcitonin, selective estrogen receptor modulator and bone formation promoter, fluoride product, vitamin D and calcium preparation, parathyroid hormone included.
And it is the first diphosphonate that got FDA's approval to be used for the treatment of postmenopausal osteoporosis and the first drug approved by FDA to treat osteoporosis in men.
Whole body bone scan [Figure 1]c and chest computer tomography (CT), [Figure 1]d identified a focal area with increased technetium-99m diphosphonate scintigram uptake over the right scapula compatible with right scapular mass and a large cauliflower-like osteosclerotic lesion exophytic from the inner area of the right scapular body.
18]F-FDG PET and technetium-99m methylene diphosphonate bone scans documenting higher sensitivity and accuracy of positron imaging in detecting bone metastases in patients affected by RCC.