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Variant of bisphosphonate.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
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Bone scintigraphy: The patients received an intravenous injection of 540-740 MBq Technetium-99m (99mTc) methylene diphosphonate. Approximately 3 hours later, they underwent a whole-body planar imaging in the anterior and posterior views on a dual-headed gamma camera (Infinia II GP & Hawkeye 4) fitted with a low-energy, all-purpose, parallel-hole collimator.
Bone scintigraphy with [.sup.99m]Tc-methylene diphosphonate revealed increased osteoblastic activity in the manubriosternal, bilateral sternocostoclavicular, and lower cervical vertebral regions (Figure 1a).
Calcification in these tumours leads to Technetium labeled Methylene Diphosphonate (Tc99m-MDP) uptake on skeletal scintigraphy.
Quantitative studies of bone with the use of 18F-fluoride and 99mTcmethylene diphosphonate. Semin Nucl Med 2001; 31:28-49.
Radionuclide diagnosis of vertebral osteomyelitis: indium-111-leukocyte and technetium-99m-methylene diphosphonate bone scintigraphy.
99m technetium methylene diphosphonate bone scintigraphy did not reveal any sacroiliac joint involvement.
Technetium-99m-methylene diphosphonate ([sup.99m]Tc-MDP) bone scan revealed a focus of intense tracer uptake in the proximal ulna [Figure 3b].
The diagnostic value of Tc-99m diphosphonate bone imaging in transient osteoporosis of the hip.
Kamperdijk, "Elimination of phagocytic cells in the spleen after intravenous injection of liposomeencapsulated dichloromethylene diphosphonate. Ultrastructural aspects of elimination of marginal zone macrophages," Virchows Archiv B Cell Pathology Including Molecular Pathology, vol.
[sup.99m]Tc-methylene diphosphonate (MDP) planar bone scan or single-photon emission computed tomography (SPECT) is widely used as noninvasive methods for detecting osseous metastases.

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