If additional signals were present in the cell, they were disomic
for autosomes (Figure 2A) and diploid for sex chromosomes (Figure 2B).
Increased incidence of disomic
sperm nuclei in a 47, XYY male assessed by fluorescent in situ hybridization (FISH).
Creen arrow showing average red (human epidermal growth factor receptor 2 [HER2]) signals, 4 to 5 per cell, with disomic
CEP17 (green) signals, whereas HER2 showed classical amplification with multiple green (HER2) signals (blue arrow) when interpreted in relation to D17S122 reference loci (original magnification X1000).
These complicated and varied phenotypes are generally thought to result from the imbalance between the expression of trisomic genes on chromosome 21 and disomic
genes on other chromosomes, resulting into abnormal gene dose.
The first is homologues chromosome segregation towards the same axis during meiosis I, leading to disomic
or nulisomic daughter cells.
GGE Biplot analysis of genotype x environment interaction in wheat-barley disomic
In this study, our aim was to eliminate an entire chromosome in human cells to generate normal disomic
cells from trisomic cells.
Sex-chromosome disomy was the primary outcome of interest because of its reproductive health impacts: a) it is the most frequent form of sperm aneuploidy and occurs twice as frequently as autosomal disomy; b) sperm that are disomic
for X or Y are capable of fertilization; and c) sex-chromosome disomy results in viable offspring.
There is a clear separation between the risk scores of trisomic and disomic
A sample was defined as 'normal disomic
' when the fluorescent ratio was ~1.0 for all loci analysed.
A detailed RFLP map of cotton, Gossypium hirsutum A- Gossypium barbadense: chromosome organization and evolution in a disomic
Duplicate loci ([IDH-3,4.sup.*] and [MDH-3,4.sup.*]) were treated as two disomic
loci with identical allele frequencies because allele variation could not be assigned to a specific locus (Allendorf & Thorgaard, 1984), although this treatment tends to give conservative estimates of heterozygosity and genetic differentiation (Krueger et al., 1989).