dissociation constant

(redirected from dissociation constants)
Also found in: Thesaurus, Medical, Encyclopedia.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.dissociation constant - the equilibrium constant for a reversible dissociation
equilibrium constant - (chemistry) the ratio of concentrations when equilibrium is reached in a reversible reaction (when the rate of the forward reaction equals the rate of the reverse reaction)
Mentioned in ?
References in periodicals archive ?
Determination of dissociation constants and specific rate constants of enzyme--substrate (or protein--ligand) interactions from rapid reaction kinetic data.
Due to the lack of information on the equilibrium dissociation constants of Fe-itaconic acid and Al-itaconic acid complexes in the literature, their pK values will be indirectly estimated in the present study.
The analysis of different flavonols showed dissociation constants between 2.
MST technology will give us the opportunity to accelerate the process of finding a suitable candidate, the method is time-consuming, Optimizable, provides a measurement of dissociation constants of bonds, stoichiometry and binding energy and allows to detect protein aggregation, which could adversely affect the relevance of the received parameters.
Summary: Thermodynamic dissociation constants (Ka) of propionic acid in 0 5 10 and 20 wt% 1- propanol-water binary mixtures have been determined between 303.
This assay in another hand provides uncooked suggestion about affinity, abundance, association rate constants, dissociation constants and binding specificity of DNA-Binding proteins.
To test this hypothesis, we characterized the binding of five LC-PCB sulfates to TTR and compared their equilibrium dissociation constants (Kd values) to those determined for their hydroxylated precursors and for [T.
2] are the HSA-bilirubin dissociation constants for 2 independent HSA-binding sites, [P.
Therefore, if [alpha] = 1, there is no difference between the enzyme-substrate dissociation constants on the first and on the second step.
The dissociation constants determined from these experiments were similar to the inhibition constants.
Dissociation constants of the analogs binding to NOS have been determined to be 15 micromolar and 50 micromolar, respectively, using double reciprocal plot analysis.
From enzyme kinetic data, enzyme-substrate dissociation constants and interactivity constants between substrates were determined.