doxorubicin


Also found in: Thesaurus, Medical, Wikipedia.

dox·o·ru·bi·cin

(dŏk′sə-ro͞o′bĭ-sĭn)
n.
An antibiotic, C27H29NO11, obtained from the bacterium Streptomyces peuceticus and used as an anticancer drug.

[Alteration of (hy)d(r)oxy + rubi(domy)cin, antibiotic from which it is derived (Latin rubidus, red, from its red crystals; see rubidium + -mycin).]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

doxorubicin

(ˌdɒksəˈruːbəsɪn)
n
an antineoplastic antibiotic used in the treatment of cancer
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.doxorubicin - an antibiotic used as an anticancer drug
antibiotic, antibiotic drug - a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

doxorubicin

n doxorubicina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
M2 PRESSWIRE-August 23, 2019-: Liposomal Doxorubicin Market To Gain Tremendous Demand Owing To Increasing Occurrence of Ovarian And Breast Cancer Till 2024 | Million Insights
Anthracyline drugs such as doxorubicin are first extracted from Streptomyces peucetius var.
The company added that the DC Bead LUMI, which is a next-generation DC Bead, is the first commercially available Radiopaque Drug-Eluting Bead that can be loaded with doxorubicin or irinotecan for the local treatment of hepatocellular carcinoma (HCC) and liver metastases from colorectal cancer (mCRC), respectively.
Eli Lilly reported that the results of ANNOUNCE, the Phase 3 study of Lartruvo in combination with doxorubicin in patients with advanced or metastatic soft tissue sarcoma, or STS, did not confirm the clinical benefit of Lartruvo in combination with doxorubicin as compared to doxorubicin, a standard of care treatment.
Doxorubicin is an anthracycline anticancer drug with highly effective chemotherapeutic agent which is used to treat various cancers, including haematological malignancies and others sarcomas [1, 2].
To overcome the current limitations, we coencapsulate doxorubicin and verapamil into gold liposomes and use a ns-pulsed laser to trigger fast intracellular drug release.
The majority of the responses with doxorubicin-based regimens were seen in patients receiving the combination of doxorubicin and ifosfamide (4/5 pts) or doxorubicin and dacarbazine (1/5 pts).
GPX-150 has been engineered specifically to retain the anticancer activity of doxorubicin while minimizing the potential for irreversible damage to the heart.
For example, the chemotherapy drug doxorubicin was shown to induce EMT in different types of cancer cells, including breast cancer, hepatocellular carcinoma (HCC), and pancreatic cancer (17-19), although the mechanism of doxorubicin-induced EMT is unclear.
Objective: To demonstrate the morphological changes in number of seminiferous tubules that are produced by anthracycline doxorubicin on the testes of mice.
Treatment with the genotoxic drug doxorubicin typically induces remodeling of actin cytoskeleton architecture; however, its effects appear somewhat controversial [17-21].