doxorubicin


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dox·o·ru·bi·cin

(dŏk′sə-ro͞o′bĭ-sĭn)
n.
An antibiotic, C27H29NO11, obtained from the bacterium Streptomyces peuceticus and used as an anticancer drug.

[Alteration of (hy)d(r)oxy + rubi(domy)cin, antibiotic from which it is derived (Latin rubidus, red, from its red crystals; see rubidium + -mycin).]

doxorubicin

(ˌdɒksəˈruːbəsɪn)
n
an antineoplastic antibiotic used in the treatment of cancer
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.doxorubicin - an antibiotic used as an anticancer drug
antibiotic, antibiotic drug - a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs"
Translations

doxorubicin

n doxorubicina
References in periodicals archive ?
GPX-150 has been engineered specifically to retain the anticancer activity of doxorubicin while minimizing the potential for irreversible damage to the heart.
PharmaMar will present the final efficacy and safety data obtained from the Phase I/II trial combining PM1183 (lurbinectedin) with doxorubicin in relapsed small-cell lung cancer during a Research Perspectives oral session, on October 16th (abstract ID9249).
For example, the chemotherapy drug doxorubicin was shown to induce EMT in different types of cancer cells, including breast cancer, hepatocellular carcinoma (HCC), and pancreatic cancer (17-19), although the mechanism of doxorubicin-induced EMT is unclear.
M2 PHARMA-May 17, 2017-Dr Reddy's gains US FDA approval to launch its doxorubicin hydrochloride liposome injection
Objective: To demonstrate the morphological changes in number of seminiferous tubules that are produced by anthracycline doxorubicin on the testes of mice.
Doxorubicin is one of the anticancer drugs, which is widely used in the treatment of various types of aggressive tumors.
Doxorubicin is a very potent cytotoxic anticancer that directly inhibits topoisomerase II and nucleic acid synthesis.
Doxorubicin (DOX) is a potent and widely used anthracycline antibiotic for the treatment of cancers.
While 3 [micro]M doxorubicin alone could not induce cell death in P388/DOX cells, concomitant treatment with doxorubicin and subtoxic concentration of medicarpin or millepurpan restored the pro-apoptotic cascade.
Cardiotoxicity was induced by single intravenous injection of 12 mg/kg of doxorubicin in a group of rabbits control group was treated with normal saline only and the rabbits of third group were pretreated with a- Tocopherol 200 mg/kg of body weight for ten days before injection of doxorubicin 12 mg/kg.
Anthracyclines, including doxorubicin are potent anticancer drugs but can cause severe chronic cardiotoxicity.