dronedarone


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dronedarone

n dronedarona
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Panelists supporting approval agreed that the indication should make clear that cardiac hospitalizations, but not mortality, were reduced in patients treated with dronedarone in the study.
A separate study is comparing postablation treatment using amiodarone or dronedarone.
A separate study compares postablation therapy with amiodarone or dronedarone.
SAN FRANCISCO -- An investigational agent, dronedarone, reduced by 24% the risk of hospitalization for cardiovascular problems or death from any cause in moderate- to high-risk patients with atrial fibrillation or flutter in the largest study of any antiarrhythmic medication for atrial fibrillation.
* Dronedarone. Now under FDA review, dronedarone is an amiodaronelike compound that lacks the iodine moiety and is safer than amiodarone.
DALLAS -- The novel investigational antiarrhythmic agent dronedarone reduced by 27% the 1-year combined incidence of hospitalization or death compared with placebo in a large group of patients with paroxysmal or persistent atrial fibrillation, Dr.
* Dronedarone. Also before the FDA, dronedarone is an amiodarone congener and the first from a line of amiodarone-like compounds that are in development.
He presented a posthoc analysis of two pivotal phase III, double-blind, randomized trials totaling 1,237 patients with atrial fibrillation: the European trial in atrial fibrillation or flutter patients receiving dronedarone for the maintenance of sinus rhythm (EURIDIS) and the American-Australian trial with dronedarone in atrial fibrillation or atrial flutter patients for the maintenance of sinus rhythm (ADONIS).
The results showed that dronedarone was "effective for heart-rate control with no evidence of amiodarone-like toxicity," Dr.
Dronedarone, a derivative of amiodarone, was designed to have less extracardiac toxicity by the elimination of amiodarone's iodine component and by making dronedarone less lipophilic, said Dr.
Another promising class III drug for chronic AF is dronedarone, a structurally close derivative of amiodarone, widely considered to be the most effective available rhythm control agent.
SAN FRANCISCO -- Dronedarone is an antiarrhythmic drug that physicians will be hearing a great deal about between now and year's end, Dr.