drug holiday


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drug holiday

n.
A usually brief period during which a drug that is typically taken on a daily basis, such as an antidepressant, is not taken or is replaced with another in order to minimize certain side effects.
References in periodicals archive ?
This is an encouraging finding because it suggests that an antipsychotic drug holiday might promote a measurable degree of cognitive recovery.
The PNP, he said, would not stop its war on drugs, otherwise 'there will be a drug holiday in our country.
Objective: To evaluate the oncologists thoughts about the positive and adverse effects of bisphosphonates, drug holiday and the awareness about BRONJ.
As part of an ERC advanced grant, my laboratory has shown that BRAF inhibitor withdrawal in melanomas that have developed resistance to BRAF inhibitors leads to a transient growth arrest that is the consequence of temporary hyperactivation of signaling through the MAP kinase pathway, explaining the so called drug holiday effect .
The symptoms often improve with a drug holiday, for instance during vacation.
That's why the recommendation is that around the 5-year point you can consider having a drug holiday or switching off the bisphosphonates.
As shown in our patients, successful treatment of this MEK inhibitor-associated cutaneous eruption can include a drug holiday and oral corticosteroid therapy, with reinstitution of the drug at a lower dose without recurrence," Dr.
Other times, patients can take a drug holiday, then restart the same statin without developing side effects.
The decision to prescribe bisphosphonates depends on several factors, including dual-energy x-ray absorptiometry (DXA) results and patient factors, and consideration for a drug holiday is warranted in each patient's care, Dr.
The researchers cautioned clinicians and patients contemplating a drug holiday after 5 years of treatment to "be aware that short-term monitoring to detect individuals at higher risk who might resume bisphosphonate therapy, or initiate another therapy, may not add to risk prediction over and above age and BMD measured at the time of discontinuation.
Pourhassan added that treatment substitution study has the potential to provide a drug holiday to patients from their daily pill regimen.