5% after announcing Monday that it plans to file an IND for lead candidate KB103, a treatment for dystrophic
epidermolysis bullosa later this month.
Last autumn, James helped national charity DEBRA (the Dystrophic
Epidermolysis Bullosa Research Association), which supports individuals and families affected by EB, launch a PS500,000 #FIGHTEB appeal to fund a special research project.
EB-101 is being developed for recessive dystrophic
epidermolysis bullosa, a rare genetic condition with no cure that is marked by widespread blistering.
ProQR is developing its RNA platform technology in areas of ophthalmology, cystic fibrosis and dystrophic
THE FOOD AND DRUG ADMINISTRATION has granted breakthrough therapy status to Abeona Therapeutics's EB-101 gene therapy program for patients with recessive dystrophic
epidermolysis bullosa, according to a company statement.
The double-blind and placebo-controlled trial randomised 169 participants with a documented diagnosis of Simplex, Recessive Dystrophic
, or Junctional non-Herlitz epidermolysis bullosa to SD-101 or placebo during a three-month primary treatment period.
Program update on the EB-101 gene therapy for recessive dystrophic
epidermolysis bullosa (RDEB) as the Company prepares to initiate a pivotal Phase 3 clinical trial, including an update on Abeonas manufacturing strategy, plans and progress in the development of its clinical and commercial grade production facility;
Myra Ali, 29, was detected with a genetic connective tissue disorder called epidermolysis bullosa (EB) that affects one out of every 20,000 births in the United States, according to the Dystrophic
Epidermolysis Bullosa Research Association of America (DEBRA).
31] undertook a study of 13 subjects (37 toe nails) and investigated the effective ness of the Cutera[TM] Nd:YAG short pulse laser in the treatment of patients with dystrophic
nails, microscopically confirmed as onychomycosis.
Three patterns of dystrophic
calcification were identified microscopically: individual neuronal mineralization, a fine granular pattern (Figure 2, panel F), and a more coarse dystrophic
pattern (Figure 2, panels A, E, G).
There are three major subtypes; simplex, junctional and dystrophic
The most common type is dystrophic
which is basically a response to injury, infection, inflammation, venous stasis and connective tissue disorders.