dystrophin

(redirected from dystrophins)
Also found in: Medical.

dys·tro·phin

 (dĭs′trə-fĭn′)
n.
A large protein that stabilizes muscle fibers by forming a link between the internal cytoskeleton and a protein complex in the plasma membrane that is connected to the extracellular matrix. Genetic mutations resulting in the absence of dystrophin cause Duchenne muscular dystrophy, and those resulting in insufficient or abnormal dystrophin cause Becker muscular dystrophy.

dystrophin

(ˈdɪstrəfɪn)
n
(Pathology) a protein, the absence of which is believed to cause muscular dystrophy
References in periodicals archive ?
Absence of dystrophin starts a chain reaction that eventually leads to muscle cell degeneration and death.
For years, scientists have been working to find the key to restoring dystrophin, but they have faced many challenges.
Dystrophin is the largest gene in the human genome, containing approximately 4,000 amino acids.