NEH is an uncommon disease described as an infiltration of neutrophils in and around the eccrine gland
. It is observed mainly in patients undergoing chemotherapy for hematologic-oncologic diseases (1-6).
Also, eccrine gland
involvement was seen by the infiltration of lymphocytes arranged predominantly around and within the eccrine glands
with syringometaplasia (figure 3d).
Linear porokeratosis and porokeratosis of Mibelli are characterized by sharply demarcated hyperkeratotic annular lesions with distinct keratotic edges but do not have eccrine gland
involvement on histopathology.
In these types, we are going to analyse the eccrine gland
had reported an association with another eccrine gland
disorder, hidrocystoma .
Eccrine hidrocystomas are benign cystic lesions which originate from eccrine gland
ducts1 predominantly located on the face - eyelid and cheek regions.2,3 They are classified into two types, namely apocrine and eccrine hidrocystomas according to their histological and presumed histogenetic derivation.
Monoclonal antikeratin antibody tests, electron microscopy, and immunohistochemical tests confirmed the intraepidermal eccrine gland
nature of this disease (2, 12).
It typically appears as a papule or solitary nodule, euchromatic or red in the sole or lateral border of the feet, corresponding to 2/3 of the cases; as with other eccrine gland
tumors, a pigmented variant of rare presentation exists (2,3) other sites affected are: the distal extremities, palms, and fingers, and less likely in the forearms, eyelids, thorax, scalp, external auditory canal, hip, gluteus, and abdomen (4-9).
By asking patients what they have been using and what the problem is, and understanding why aluminum chloride failed them in the past, he has found that he could get "four out of five of these patients to be happy and not perspiring with topical antiperspirants, often prescription strength, even though virtually all of them are ready to go for neurotoxins when I first meet them." The remaining 20% will need botulinum toxin A to block nerve endings from communicating with the smooth muscle in the eccrine gland
, which is required to push sweat out of the gland.
secretions from the fingers, hands, and feet are both organic and inorganic, but only organic materials are secreted from the sebaceous glands.
Main clinical feature of HED is sparse or absent eccrine gland
as well as hypotrichosis and oligodentia with peg-shaped teeth with incisor and/or canine teeth mainly affected which looks conical and pointed and sometimes is the only obvious abnormality.
Although not unique to KAs, histology may commonly show reactive proliferation of eccrine gland
ducts beneath the tumor lobules.