clotrimazole, miconazole, econazole
and ketoconazole) are generally well tolerated and efficacious when used twice daily for at least 2 weeks.
3% Terbinafine 38% 59% 70% TABLE 3 Agents Available for the Treatment of Tinea Pedis Agent Formulation(s) Mycological Cure Naftifine 2% Cream, gel Once a day x 2 weeks Luliconazole 1% Cream Once a day x 2 weeks Terbinafine 1% Cream, gel, spray Once a day x 1-4 weeks (gel) Twice a day x 1-4 weeks (cream, spray) Butenafine 1% Cream Once a day x 4 weeks Oxiconazole 1% Cream, lotion Once/twice a day x 4 weeks Naftifine 1% Cream, gel Once a day x 4 weeks (cream) Twice a day x 4 weeks (gel) Econazole
1% Cream, foam Once a day x 4 weeks Tolnaftate 1 % Cream, gel, Twice a day x 2-6 weeks powder, spray Sertaconazole Cream Twice a day x 4 weeks nitrate 2% Ciclopirox 0.
Proper treatment of tinea corporis consists of antifungal creams containing ketoconazole, econazole
, or naftifine on non-hair-bearing areas.
The current guidance on candidal nappy rash recommends treatment with imidazole cream (clotrimazole, econazole
or miconazole) and that no barrier preparation is used until the infection has resolved (NICE, 2013).
azole antifungals in this pharmacologic class: clotrimazole (Lotrimin), econazole
(Spectazole), ketoconazole (Kuric), miconazole (Micatin), oxiconazole (Oxistat), sertaconazole (Ertaczo), and sulconazole (Exelderm).
A systematic review comparing intravaginal treatment with nitroimidazoles (clotrimazole, miconazole, econazole
, and butoconazole) to oral fluconazole or itraconazole found that both treatments were equally effective in the short and long term, with cure rates of 82% vs.
M2 EQUITYBITES-November 5, 2013-IGI Laboratories receives approval for site transfer of econazole
nitrate cream(C)2013 M2 COMMUNICATIONS http://www.
M2 PHARMA-November 5, 2013-IGI Laboratories receives approval for site transfer of econazole
nitrate cream(C)2013 M2 COMMUNICATIONS
5 mg-kg-day IV for 7-14 days Caspofungin 50 mg-day IV or anidulafungin 200 mg-day IV or micafungin 150 mg-day IV for 7- 14 days Vulvovaginal Topical candidiasis Topical therapy with azoles for 3-7 days or nystatin for 10-14 days: Butaconazole 2% cream, 5 g/day Clotrimazole 1% cream, 5 g/day Clotrimazole vaginal tablets, 500 mg/day Miconazole 2% cream, 5 g/day Miconazole 100 mg, 200 mg or 1200 mg (single dose) vaginal suppositories Econazole
150 mg tablets or suppository Terconazole 0.
Antifungal agents are either polyenes (nystatin and am-photericin B) or azoles which are classified into: imidazoles (clotrimazole, econazole
, fenticonazole, isoconazole, ketocon-azole, miconazole, sulconazole, tioconazole); and triazoles (fluconazole, itraconazole).
polyenes (eg amphotericin-B) and azoles (eg econazole
and fluconazole) (Table 2).