ectoenzyme


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ectoenzyme

(ˌɛktəʊˈɛnzaɪm)
n
(Biochemistry) any of a group of enzymes secreted from the cells in which they are produced into the surrounding medium; extracellular enzyme. Also called: exoenzyme
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2008) Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs.
Heterotrophic bacteria in the northern Adriatic Sea: seasonal changes and ectoenzyme profile.
5'-nucleotidase is an intrinsic membrane glycoprotein, present as an ectoenzyme in a wide variety of mammalian cells and it hydrolyzes extracellular AMP to adenosine and represents the major control point for extracellular adenosine levels and is a regulator of the adenosine signaling pathway.
A key indicator of osteoblast maturation is the membrane-bound ectoenzyme alkaline phosphatase (ALP).
A gene expression study carried out by Corton et al (66) with omental adipose tissue from PCOS women showed overexpression of ectoenzyme nucleotide pyrophosphate phosphodiesterase 1 (ENPPI), which is a negative regulator of INSR tyrosine kinase activity and the regulatory p85[alpha] subunit of PI3K which resulted in decreased PI3K activity.
CD38 is an ectoenzyme important to the metabolism of activated T lymphocytes, an adhesion receptor involved in the migration of lymphocytes into peripheral tissues and a signalling molecule responsible for T cell co-stimulation and B cell maturation [33,34].
Aminopeptidase N (APN) is found as a soluble cytoplasmic enzyme and a membrane-bound ectoenzyme; the ectoenzyme form is attached to epithelial cells of intestinal brush borders and respiratory tracts.
Just one ectoenzyme introduced into the cells which were going to form the head of the tadpole created several eyes.