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Any of a group of substances that are derived from arachidonic acid, including leukotrienes, prostaglandins, and thromboxanes.

[eicosan(e), chemical name (Greek eikosi, twenty, from its twenty carbon atoms; see wīkm̥tī- in Indo-European roots + -ane) + -oid.]


any of a group of compounds, including the leukotrienes and the prostglandins, which are produced by the oxygenation of essential fatty acids and which are involved in a range of physiological processes, including inflammation and immunity
References in periodicals archive ?
2][alpha] lies upstream of eicosanoid biosynthesis in many situations.
sativa inhibits eicosanoid generation in leukocytes and lipid peroxidation.
Results: Cur treatment of acute Chagas mice enhanced survival and proved to hinder relevant inflammatory processes in the heart, including leukocyte recruitment, activation of the eicosanoid pathway and BNP overexpression, without modifying parasite burden in the organ.
Exhaled breath condensate eicosanoid levels associate with asthma and its severity.
Apart from Eicosanoid dependent mechanism, EFA also affects cellular signalling by making lipid rafts and altering gene expression by their effect on transcription factor and blockage of TNF [alpha] (Tumour Necrosis Factor), IL (Interleukin) and LT (Leukotriene), which is responsible for improved lacrimal secretion (Figure 2).
Mollnes, Differential effect of heparin coating and complement inhibition on artificial surface-induced eicosanoid production, The Annals of Thoracic Surgery, 79(3), 917-923 (2005).
Oral green tea catechin metabolites are incorporated into human skin and protect against UV radiation-induced cutaneous inflammation in association with reduced production of pro-inflammatory eicosanoid 12-hydroxyeicosatetraenoic acid.
For quantitative catecholamine and eicosanoid determination, the limit of detection or quantification was determined from the daily calibration curve, and absolute quantification was performed with stable isotope-labeled standards.
Dysregulation of eicosanoid biosynthesis has been linked to inflammation, infertility, allergy, degenerative diseases, atherosclerosis, ischemia, metabolic syndrome, and, most importantly, to cancer [6].
As a rule, diet fatty acids may affect the immune response by conditioning 1) plasmatic membrane fatty acid composition and its subsequent effects on the membrane's physical qualities (TOCHER, 1995), 2) cytokines and eicosanoid production, synthesized from the precursors eicosapentaenoic (20:5 n-3, EPA) and arachidonic (20:4 n-6, ARA) acids, which are the key cell messengers in the inflammation process (ROWLEY et al.
These mechanisms of n-3 PUFA regulate inflammation via the eicosanoid pathway[sup.