elastase


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e·las·tase

 (ĭ-lăs′tās, -tāz)
n.
Any of a class of enzymes that catalyze the hydrolysis of elastin, especially one that is found in pancreatic juice.

elastase

(ɪˈlæsteɪs)
n
(Biochemistry) an enzyme that digests elastin
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.elastase - a pancreatic enzyme that catalyzes the hydrolysis of elastin
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
Translations

e·las·tase

n. elastasa, enzima que cataliza la digestión de las fibras elásticas, esp. en el jugo pancreático.
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for POL6014, a clinical stage selective inhibitor of human neutrophil elastase with the potential to treat cystic fibrosis (CF) and other neutrophilic pulmonary diseases such as non-cystic fibrosis bronchiectasis (NCFB), alpha-1 antitrypsin deficiency (AATD) and primary ciliary dyskinesia (PCD).
POL6014 is a clinical stage selective inhibitor of human neutrophil elastase with the potential to treat cystic fibrosis (CF), as well as other neutrophilic pulmonary diseases, such as non-cystic fibrosis bronchiectasis (NCFB), alpha-1 antitrypsin deficiency (AATD) and primary ciliary dyskinesia (PCD).
Trypsin, chymotrypsin, and elastase activities in extracts of 5 mg total protein from larval guts of laboratory (NL, US), field (GTO), and Xentari-selected (USX) strains were compared.
UK-based biopharmaceutical company Mereo BioPharma Group plc (AIM: MPH) has reached an agreement with UK-based drugmaker AstraZeneca (NYSE: AZN) for an exclusive license, including an option to acquire, AZD9668, an oral inhibitor of neutrophil elastase, the company said on Monday.
This financing complements the recent CARB-X grant of up to $8,9 million awarded to Antabio in July 2017 to support the company's Elastase Inhibitor program (PEI) for the treatment of chronic Pseudomonas infections in Cystic Fibrosis patients.
These new zonulin ELISAs expand ALPCO's current gastrointestinal assay panel to investigate bile acids, calprotectin, alpha-1 antitrypsin, lysozyme, secretory IgA and pancreatic elastase.
Meantime, all the isolates (1-10) were evaluated for their anti-oxidative and inhibiting neutrophil elastase activities by the bioassays in vitro.
Elastase released by microorganisms is an important virulence factor in several types of infections, [15] and the invasive effect of elastase by Pseudomonas aeruginosa has been well documented.
screened 50 Korean plants to identify natural sources of elastase and hyaluronidase inhibitors in 2010.
Faecal elastase levels were adequate (>500 pg/g).
They also secrete several cytokines (TNF-[alpha], IL-8, IL-1[beta]) and extracellular matrix degrading enzymes such as elastase and matrix metalloproteinases 2 and--9 (MMP-2 and 9).