Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.


 (ĕn′də-dûrm′) also en·to·derm (ĕn′tə-)
The innermost of the three primary germ layers of an animal embryo, developing into the gastrointestinal tract, the lungs, and associated structures. Also called hypoblast.

en′do·der′mal adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
Enterogenous cysts are endodermal in origin, arise from the hindgut, and are lined with columnar mucinous epithelium.
Epidermoid cysts are lined with stratified squamous epithelium and teratoid also contain skin adnexa, along with mesodermal and endodermal elements (muscles, bones, respiratory and gastrointestinal tissues) [1, 2, 4].
In some cases, engulfed algae were phagocytized by the endodermal epithelial cells (digestive cells) and formed symbiotic relationships with the host polyps.
They show plasticity with their ability to differentiate into tissues of mesodermal, endodermal, and ectodermal origin, including skin.7,8 Bone marrow transplantation as one of kind of stem cells therapy initially was used in conditions like leukemias, lymphomas, other hemoglobinopathies etc.
(13) described GCC as a neoplasm of endodermal origin arising from root cells located in the basal part of the gland and crypta.
Immature teratoma can be excluded on the basis of age as these tumours most commonly occur in the first three decades of life and are almost nonexistent after menopause, and contain embryonal neuroectodermal elements and endodermal derivates in almost all cases.
MCTs include tissues of ectodermal (eg., skin, hair follicles, sebaceous glands), mesodermal (eg., muscle, urine) and endodermal origin (eg., lung, gastrointestinal) (3).
The epithelium of the small intestine is endodermal in origin.
Lungs develop embryologically from the endodermal cells similar to the gastrointestinal tract and have similar cells producing several hormonal peptides (11).
Colloid cysts originate when ectopic endodermal elements migrate into the velum interpositum during embryogenesis.
The researchers first used a multi-step process of genetic and biochemical manipulation that included the genes FGF, TGF and WNT, which transformed human induced pluripotent stem cells (iPS) into CDX2-positive posterior gut endodermal progenitor cells (PGECs).