Ménière's disease

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Mé·nière's disease

A pathological condition of the inner ear characterized by dizziness, ringing in the ears, and progressive loss of hearing.

[After Prosper Ménière (1799-1862), French physician.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

Menière's disease

Fluid accumulates in the inner ear, causing deafness, vertigo, and tinnitus. The cause of the fluid increase is usually not known.
Dictionary of Unfamiliar Words by Diagram Group Copyright © 2008 by Diagram Visual Information Limited
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Noun1.Menière's disease - a disease of the inner ear characterized by episodes of dizziness and tinnitus and progressive hearing loss (usually unilateral)Meniere's disease - a disease of the inner ear characterized by episodes of dizziness and tinnitus and progressive hearing loss (usually unilateral)
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Similarly, AI technologies are used in determining the prognosis of sudden sensorineural hearing losses in otology, in the imaging of endolymphatic hydrops, and in identifying the phenotypes of hearing loss (7).
The etiology is, in most cases, unknown and may include infections, vascular accidents, traumas, tumors, endolymphatic hydrops, and autoimmune disorders Recovery depends on several factors, including age, associated symptoms such as tinnitus and vertigo, severity of hearing impairment, and the time lapse between the onset and treatment [1]
(2) The pathogenesis may feature disturbance of cochlear fluid homeostasis and/or endolymphatic hydrops of the membranous labyrinth.
Contrast-enhanced magnetic resonance imaging (MRI) revealed that four had endolymphatic hydrops (EH), which might create auditory or vestibular symptoms [23].
The deposition of immune complexes in the vascular stria causes damage to the capillary epithelium with alterations in vascular permeability that can cause endolymphatic hydrops, destruction of hair cells, collapse of the Reissner membrane, and membrane tectoria distortion [15].
Numerous studies have suggested that the disruption of this barrier can result in imbalance of local ionic homeostasis [35, 36], reduced drug entry [36], endolymphatic hydrops [40], and hearing loss [41].
Clinical presentation includes audiological and vestibular symptoms that often mimic those of other middle and inner ear disorders such as otosclerosis [4, 5] and endolymphatic hydrops (EH) [6].
In addition, from the pathophysiological point of view, different from the vascular findings[sup][23] in the cochlea in patients with presbycusis, the cause of Meniere's disease is recognized as the hydrolabyrinth with evidence.[sup][24] The degree of endolymphatic hydrops in Meniere's disease has its regulated changes during progression.
The most well-known aspect of MD is the presence of endolymphatic hydrops (ELH), a hallmark of the disease which can be confirmed by pathology postmortem [20,49].
Pathophysiology of Meniere's Syndrome: Are Symptoms Caused by Endolymphatic Hydrops? Otology & Neurotology 2005;26:74-81.
Meniere's disease or endolymphatic hydrops is due to an increase in endolymph pressure resulting in inappropriate nerve excitation which will give rise to the triad of vertigo, fluctuating hearing loss and tinnitus.
Comment: Meniere's disease (also called idiopathic endolymphatic hydrops) is characterized by an excess of fluid in the inner ear, which results in disturbances of balance and hearing.