David Dodd, Chairman and CEO of Aeterna Zentaris, commented, This positive second recommendation from the DSMB is an important milestone since it supports our continuation of the ZoptEC Phase 3 trial in endometrial cancer
until its completion.
David Dodd, Chairman and CEO of Aeterna Zentaris, commented, "This positive second recommendation from the DSMB is an important milestone since it supports our continuation of the ZoptEC Phase 3 trial in endometrial cancer
until its completion.
Adds Russell Broaddus, professor of pathology: 'The identification of this second cluster of patients with endometrial cancer
helps to refute longstanding teachings that young, obese patients universally have endometrial cancers
that are estrogen-driven and thus have a good prognosis.
Crude incidence of endometrial cancer
was 12 per 10,000 person-years for nonusers and 8 per 10,000 years for bisphosphonate users (bisphosphonate users: hazard ratio, 0.
The endometrial cancer
incidence rate among women in the study who reported ever using nitrogenous bisphosphonates was 8.
is one of the more prevalent cancers and is a common cause of cancer death worldwide.
First author Kristy Ward, senior gynecologic oncology fellow at UC San Diego, said that estimating from various studies that looked at increasing BMI and endometrial cancer
risk, a woman with a Body Mass Index (BMI) of 40 would have approximately eight times greater risk of endometrial cancer
than someone with a BMI of 25.
Thus, the utility of this detection approach for endometrial cancer
will require validation of both the sampling technique and the gene panel through studies on women with and without cancer who have not yet undergone endometrial sampling.
If your doctor suspects endometrial cancer
you will have an ultrasound scan.
That suggests drugs for those other cancers might prove useful in treating these types of endometrial cancer
Likewise, endometrial cancer
is the most commonly diagnosed gynaecologic cancer, the CDC said, and is best treated when caught early.
To determine which genes are altered in serous endometrial cancer
, senior author Daphne W.