endoplasmic reticulum

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Related to endoplasmic reticulum: Smooth endoplasmic reticulum

endoplasmic reticulum

A membrane network within the cytoplasm of cells involved in the synthesis, modification, and transport of cellular materials.

endoplasmic reticulum

(Biology) an extensive intracellular membrane system whose functions include synthesis and transport of lipids and, in regions where ribosomes are attached, of proteins

endoplas′mic retic′ulum

a network of tubular membranes within the cytoplasm of the cell, occurring either with a smooth surface (smooth endoplasmic reticulum) or studded with ribosomes (rough endoplasmic reticulum), involved in the transport of materials..

en·do·plas·mic reticulum

A network of membranes within the cytoplasm of many cells that is important in protein synthesis and involved in the transport of cellular materials. All organisms except bacteria have at least one endoplasmic reticulum in their cells. See more at cell.

endoplasmic reticulum

A system of internal membranes in a cell.

en·do·plas·mic re·tic·u·lum

n. retículo endoplásmico, sistema de canales en los cuales se llevan a cabo las funciones de anabolismo y catabolismo de la célula.
References in periodicals archive ?
The mammalian endoplasmic reticulum stress response element consists of an evolutionarily conserved tripartite structure and interacts with a novel stress-inducible complex.
WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells.
In the case of people with mutated LSS, the investigators found that the enzyme actually spreads outside of the endoplasmic reticulum and into the cytosol, the intracellular fluid.
The endoplasmic reticulum is the part of the cell involved in the processing of protein.
Some studies have shown that endoplasmic reticulum stress (ERS) signaling pathways contribute to the development of insulin resistance and hepatic steatosis in NAFLD.[9],[10],[11],[12] X-box binding protein-1 (XBP-1) is a major transcription regulator of the unfolded protein response (UPR), mediating adaptation to ERS.[13] Here, we hypothesized that XBP-1 plays a role in the process of fructose-stimulated lipogenesis in HepG2 cells.
Effects of intermittent ladderclimbing exercise training on mitochondrial biogenesis and endoplasmic reticulum stress of the cardiac muscle in obese middle-aged rats.
This study effectively shows for the first time that blue light causes damage to the retinal tissue by not only promoting oxidative stress, which has been reported earlier, but also increases stress in the endoplasmic reticulum.
These miRNAs are also involved in autophagy by regulating the unfolded protein response (UPR) during endoplasmic reticulum stress, which contributes to IBD intestinal fibrosis.
Inflammation and Endoplasmic Reticulum Stress Induce GDF15 Expression.
The endoplasmic reticulum (ER) is responsible for modifying and folding proteins correctly, serving as a quality control system to maintain protein homeostasis [8].
Herein, we demonstrated the effect of chronic inflammation, oxidative stress, and prolonged endoplasmic reticulum stress on MetS development, as well as the potential of cellular therapy on MetS-associated diseases, especially type 2 diabetes treatment.

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