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n. pl. e·pis·ta·ses (-sēz′)
1. An interaction between nonallelic genes in which the genotype at one locus affects the expression of alleles at another locus.
2. A film that forms over the surface of a urine specimen.
3. The suppression of a bodily discharge or secretion.

[Greek, stoppage, from epistanai, to stop, check : ep-, epi-, epi- + histanai, to place; see stā- in Indo-European roots.]

ep′i·stat′ic (ĕp′ĭ-stăt′ĭk) adj.


1. (Medicine) obsolete scum on the surface of a liquid, esp on an old specimen of urine
2. (Medicine) med the arrest or checking of a bodily discharge, esp bleeding
3. (Genetics) genetics Also called: hypostasis the suppression by a gene of the effect of another gene that is not its allele
[C19: from Greek: a stopping, from ephistanai to stop, from epi- + histanai to put]
epistatic adj


(ɪˈpɪs tə sɪs)

n., pl. -ses (-ˌsiz)
a form of interaction between nonallelic genes in which one combination of such genes has a dominant effect over other combinations.
[1915–20; probably after epistatic (1907) (probably epi- + static, taken as meaning “standing above”)]
ep•i•stat•ic (ˌɛp əˈstæt ɪk) adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.epistasis - the suppression of a gene by the effect of an unrelated gene
biological process, organic process - a process occurring in living organisms
References in periodicals archive ?
The E (extension) gene is responsible for allowing the deposit of pigment into the fur, which means it can overcome the phenotype of another gene in a process called epistasis. The dominant E gene ("E") allows the pigment to be deposited normally into the fur, but its mutated recessive gene ("e") prohibits the depositing of pigment.
Keywords: Bread wheat, gene action, epistasis, generation mean analysis.
Interactions of DNA-markers called the epistasis are also considered in the framework of the proposed modification.
Yes 42 (1901), 2.2 Did not reply -- (2) Previous episodes of epistasis? Yes 453 (1901), 23.8 Did not reply -- (3) Bleeding under the skin?
It was found that classical risk alleles for MS do not interact outside the HLA region and that, within HLA, the interaction by epistasis is low.
This shows average RF values outside the upper and lower resistance limits of the progenitors, suggesting the occurrence of an additional gene involved in the determination of resistance or presence of epistasis. In their study of inheritance of resistance to potyvirus Pepper yellow mosaic virus (PepYMV) in tomato plants, JUHASZ et al.
This type of epistasis advocate for searching desirable specific cross combinations.
Tsai et al., "A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility," Journal of Theoretical Biology, vol.
More and more studies have shown that epistasis exists in SNPs interaction.