The second type of reaction, erythema nodosum
leprosum, typically occurs in pregnant females and patients younger than 40 years of age with borderline lepromatous or lepromatous leprosy.
The necrotic lesions of the brown recluse spider bite can mimic other diseases, including erythema chronicum migrans, Stevens-Johnson syndrome, Lyell's syndrome (toxic epidermal necrolysis), erythema nodosum
, erythema multiforme, herpes simplex infection, purpura fulminans, diabetic ulcer, bedsore, poison oak and poison ivy reactions, gonococcal arthritic dermatitis, urticaria, pyoderma, and cellulitis.
Examples of nonspecific lesions include erythema nodosum
(17%), clubbing, calcinosis cutis, and erythema multiforme.
, an allergic reaction to a strep throat or a viral infection, or possibly drugs.
Paraneoplatic erythema nodosum
(EN) is a type of panniculitis that is observed idiopathically or secondarily to drugs, infections, and rheumatic diseases.
Reported complications include keratitis, occasional corneal perforation, and lymph node suppuration; tonsillitis, cellulitis in nearby skin tissue, retinitis, erythema nodosum
, and progression to systemic disease occur less frequently (3-7).
This applicant is seeking authorization to market a generic version of thalidomide 200 mg tablets in the United States for the acute treatment of cutaneous manifestations of moderate to severe erythema nodosum
Sarcoidosis, acne, erythema nodosum
, tattoo intolerance, and atopic dermatitis are among inflammatory consequences, Dr.
Key Words: erythema nodosum
, Lofgren syndrome, old age, sarcoidosis, uveitis
The combination of erythema nodosum
, periarticular ankle inflammation, and mediastinal lymphadenopathy is designated as Lofgren's syndrome, which usually has a self-limiting course with spontaneous resolution.
Secondary manifestations include erythema nodosum
and reactive arthritis (1).
Thalidomide is indicated for the acute treatment of cutaneous manifestations of moderate to severe erythema nodosum
leprosum (ENL) and as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence.