ethacrynic acid


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eth·a·cryn·ic acid

 (ĕth′ə-krĭn′ĭk)
n.
A compound, C13H12Cl2O4, used as a diuretic primarily to treat severe edema.

[eth(yl) + acry(lic) + (phe)n(yl) + -ic.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.ethacrynic acid - diuretic (trade name Edecrin) used to treat edema
diuretic, diuretic drug, water pill - any substance that tends to increase the flow of urine, which causes the body to get rid of excess water
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References in periodicals archive ?
losartan, various diuretics, hydrochlorothiazide furosemide, ethacrynic acid), corticosteroids, alcohol, or tobacco were excluded from the study, in both the AD and control groups.
Gap junctions in the stria vascularis and effects of ethacrynic acid. Hear Res 1984; 13: 189-200.
The acute effects of furosemide, ethacrynic acid and chlorothiazide on the renal tubular handling of uric acid in the chicken.
It has been reported that a GST inhibitor (ethacrynic acid, EA) combined with alkylating agents (Chl and thiotepa) for the treatment of tumor showed some success [91].
The most recognized CLIC1 inhibitor is IAA-94, known as a glutathione transferase (GST) binding molecule [16], and based on ethacrynic acid. Similarly, it is not entirely surprising that the CLICs are members of the GST superfamily.
Enzymatic assays with 1-Chloro 2,4-dinitrobenzene (CDNB), ethacrynic acid (EA), sulfobromophthalein (BSP), p-nitrobenzyl chloride (NBC), trans-4-phenyl-3-buten-2-one (PBO) [16], and 3,4-Dichloronitrobenzene (DCNB) [17] were determined according to protocols described in the respective articles.
The xenobiotic compounds used for the inhibition bioassays were: bromosulfalein (Dow AgroSciences LLC, Indiana, USA), ethacrynic acid, 97% diethyl maleate, 97% tetraethylthiuram disulfide, and 94% curcumin (all from Sigma, St.
Drugs included in this category are furosemide, bumetanide, ethacrynic acid and tosemide.
He was prescribed furosemide for less-than-expected urine output despite having received several doses of ethacrynic acid (Edecrin).
For patients who are allergic to sulfa-containing diuretics, doctors sometimes prescribe triamterene, spironolactone, amiloride, or ethacrynic acid. These diuretic medications do not contain sulfa.