Furfuryl alcohol (FA) and carbonyl compounds, including acetaldehyde, acrolein, formaldehyde, furfural and ethyl carbamate
may form adducts with the DNA due to their electrophilic nature.
Controlling the FDR at 0.1, notable positive associations were for 1,4-dioxane, bromoform, dibenzofurans, glycol ethers, methyl ferf-butyl ether (MTBE), and propionaldehyde; whereas 1,4- dichlorobenzene, 4,4'-methylene diphenyl diisocyanate (MDI), benzidine, and ethyl carbamate
(urethane) were inversely associated with an ASD diagnosis.
(Urethane [C.sub.2][H.sub.5]OCON[H.sub.2]) is a naturally occurring ester that is common in many fermented foods and alcoholic beverages as it can be generated during the fermentation/distillation process.
(EC) is largely found in various fermented food products, tobacco, and alcoholic beverages .
High initial YAN values may also lead to increased concentrations of ethyl carbamate
, according to a recent report from Cornell University.
It presents summaries, critical reviews, and evaluations of evidence on the carcinogenicity of alcohol and ethyl carbamate
, drawing on published epidemiological studies, cancer bioassays in experimental animals, mechanistic data, and meta-analyses commissioned by IARC, plus data from government agency reports and doctoral theses.
Despite concerns about potential harms from the chemical composition of unrecorded alcohol, there are surprisingly few data on the problem in the European Region (5, 7) Pilot studies with limited numbers of samples conducted in Lithuania, Hungary and Poland (4, 6, 8) pointed to several possible problems especially relating to a higher alcoholic strength of unrecorded alcohol as well as ethyl carbamate
contamination in home produced fruit spirits.
Over the past 15 years I have employed cutting-edge technologies to improve wine yeasts that will prevent the formation of allergens and ethyl carbamate
(EC), a carcinogen found in wines.
Beer, beef and mushrooms contain carcinogens such as hydrazine, furocoumarin and ethyl carbamate
. Fish, meats and cereals contain arsenic.
Elsewhere, EFSA is to investigate human health risks caused by the contaminant ethyl carbamate
in all alcoholic drinks, focusing particularly on its presence in stone fruit brandies.
Well-known brand names of 10-year-old malt whisky contain higher concentrations of a dangerous chemical called ethyl carbamate
that experts have branded a "potential carcinogen".
Research commissioned by the Government's Food Standards Agency shows famous 10-year-old whiskies contain more ethyl carbamate
than younger brands.