The DO ES lines have been shown to be euploid
and stable (T.
embryos appear to have the greatest potential for pregnancy and represent a clear predictive factor for IVF success.
Penzias and fellow committee members reviewed national data from 2013 that showed similar pregnancy rates for women aged 42 years and younger who received a single euploid
blastocyst or two untested blastocysts.
In the euploid
group, reversed flow in the DV was observed in 5.
In this analysis, it was assumed that euploid
cases and cases with CNAs followed the same pattern regarding the differences in the fragment size distributions between fetal and maternal cell-free DNA.
FISH-based procedure for screening aneuploid embryos has a significant rate of misdiagnosis and also in vitro fertilized embryos have high level of mosaicism, therefore many of the euploid
embryos are misdiagnosed with aneuploid.
embryos have a higher chance of implantation, and the resulting pregnancies have a lower chance of miscarriage.
In a case diagnosed as complete trisomy 9 by conventional cytogenetic techniques, fluorescence in situ hybridization (FISH) studies of metaphase and interphase blood cells and skin fibroblasts could identify the presence of euploid
and trisomy 9 cells.
Of the 10 embryos subjected to array CGH, 2 failed to amplify, 2 were euploid
, 4 were aneuploid and 2 had unbalanced translocations.
cells (2n=40) with well spread chromosomes were selected and 40 metaphase per each animal were examined microscopically for analysis the frequency of SCEs.
18) All 32 aneuploid and 197 euploid
calls were correct, including trisomy 21 (n = 25; sensitivity, 100% [confidence interval (CI), 86.
Supposing that all triploid eggs could complete meiosis normally and only euploid
progeny could survive, viable offspring with a frequency of 3.