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Related to exophthalmos: Graves disease


also ex·oph·thal·mus  (ĕk′səf-thăl′məs)
Abnormal protrusion of the eyeball.

[From Greek exophthalmos, with prominent eyes : ex-, outside; see exo- + ophthalmos, eye; see okw- in Indo-European roots.]

ex′oph·thal′mic adj.


(ˌɛksɒfˈθælmɒs) ,




(Pathology) abnormal protrusion of the eyeball, as caused by hyperthyroidism. Also called: proptosis or ocular proptosis
[C19: via New Latin from Greek, from ex-1 + ophthalmos eye]
ˌexophˈthalmic adj


or ex•oph•thal•mus

(ˌɛk sɒfˈθæl məs)

also ex`oph•thal′mi•a,

protrusion of the eyeball from the orbit, caused by disease or injury.
[1870–75; < New Latin < Greek exóphthalmos with prominent eyes =ex- ex-3 + ophthalmós eye]
ex`oph•thal′mic, adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.exophthalmos - protrusion of the eyeball from the socket
hyperthyroidism, thyrotoxicosis - an overactive thyroid gland; pathologically excessive production of thyroid hormones or the condition resulting from excessive production of thyroid hormones
exophthalmic goiter, Graves' disease - exophthalmos occurring in association with goiter; hyperthyroidism with protrusion of the eyeballs
symptom - (medicine) any sensation or change in bodily function that is experienced by a patient and is associated with a particular disease
References in periodicals archive ?
Abstract: A 25-year-old female macaroni penguin (Eudyptes chrysolophus) was diagnosed with exophthalmos secondary to retrobulbar neoplasia through use of computed tomography (CT).
Serum) TSI: Thyroid-stimulating immunoglobulin binds to tissues in the eyeballs and beneath the skin, contributing to exophthalmos (protruding eyes) and pretibial myxedema (skin thickening on legs).
He had a round, ruddy face with slight exophthalmos and rightsided facial droop (both of which preceded his current illness).
Exophthalmos persists after treatment and therefore does not confirm new hyperthyroidism in the absence of other features.
LIPO-102 (Salmeterol Xinafoate and Fluticasone Propionate for Injection) is currently under development for the treatment of symptomatic exophthalmos (protrusion of the eye from the orbit) associated with thyroid-related eye disease (the thyroid condition is also known as Graves' Disease).
Therefore, clinical manifestations could include exophthalmos, interstitial lung disease, diabetes insipida, retroperitoneal fibrosis, and pericardial thickening.
5,6) Other manifestations, which are usually related to the degree of tumor extension, can include headache, dizziness, focal neurologic deficits secondary to direct tumor extension, eye and/ or facial pain, expectoration of tissue, epiphora, vision loss, exophthalmos, and anosmia.
Effects Exophthalmos may restrict eye movement and cause double vision.
Erdheim-Chester disease is generally bilateral and symmetric and may be associated with interstitial lung disease, xanthogranulomas in the skin, exophthalmos, and diabetes insipidus.
Symptomatology reported in these cases included an increase in intraocular pressure, optic disc hemorrhage, exophthalmos, blindness, eye pain, orbital and eyelid edema, reduced visual acuity, hypersensitivity reaction, swelling, tenderness, and inflammation.
The radiological evaluation of the exophthalmos with cranial CT revealed bilateral retro-orbital pseudotumors, although the thyroidstimulating hormone level was normal (Figure 4).
An intermediate form, Hand-Shuller-Christian disease, is composed of the triad of calvarial lesions, diabetes insipidus, and exophthalmos.