exosome


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ex·o·some

 (ĕk′sō-sōm′)
n.
1. A tiny vesicle created and released from the plasma membrane of various types of cells, especially immune cells, and capable of inducing antigen-specific immune responses.
2. A cellular protein complex containing enzymes that degrade nuclear and cytoplasmic RNA.
References in periodicals archive ?
A copper mesh was placed on a clean wax plate, and 30 [micro]l of the exosome suspension was added.
However, Currently the process of exosome isolation and detection is not only highly inefficient, But also technically challenging and inaccessible to hospital laboratories, Clinical facilities and resource-poor settings.
The new study builds upon a series of previously published studies in which NX Prenatal has demonstrated that the enrichment of exosome and microvesicle particles from maternal blood and subsequent proteomic analysis enables risk stratification of spontaneous preterm birth in the first trimester of pregnancy.
The new patent applications expand the scope of the Exclusive License Agreements to enable Capricor to develop new therapeutic indications for its cellular and exosome therapies in Duchenne muscular dystrophy, ventricular tachyarrhythmia, cancer and age-related disorders.
According to the terms of the contract, both parties will perform comprehensive in vitro and in vivo research with Evox's exosome technology in return for undisclosed financial considerations.
This presentation will examine the translational applications of exosome research, including biomarker discovery and drug delivery.
Previous research has demonstrated that exosome contents can serve as markers for different types of cancer, neurodegenerative conditions, kidney disease, foetal abnormalities and other disorders.
It includes expanded coverage of acute lymphoblastic leukemia; revised diagnostic criteria for fluorescent in situ hybridization; enhanced information on flow cytometry; new coverage of genetic screening, circulating DNA analysis, RT-PCR (reverse transcription polymerase chain reaction), exosome analysis, and evaluation of epigenetic abnormalities; and new chapters on hemostasis and platelets, as well as plasma cell disorders and benign diseases of leukocytes, the spleen, and immunoglobins.
Our own research in Swansea is investigating the use of exosomes and exosome-like synthetic nanoparticles in combatting ovarian and endometrial cancer.
Prior to injection, the exosomes were fluorescently labelled allowing the researchers to track the delivery of the exosome cargo into the retinal ganglion cells.
Interrogating exosome miRNA in bladder cancer differential expression by disease status
One of the important developments that we are attempting in this collaboration is to have the basic grounds to identify exosome signatures that can be there very early on before symptoms appear or before a disease becomes worse," said Dr.