The consortium will investigate which factors of the exposome
are important for health and how these factors work.
Initiatives have included collaborations across a number of application areas -- for example, to develop the first-ever exposome
data warehouse integrating environmental exposure and clinical data for large-scale health research -- as well as efforts to develop resources helpful across application areas, such as a licensing model and ecosystem for data sharing.
B vitamins and pollution, an interesting, emerging, yet incomplete picture of folate and the exposome
. Proc Natl Acad Sci USA 2017;114(20):E3878-E3879.
This article seeks to provide an integrated understanding of the totality of exposome
factors in human health by focusing on the contributions of personal care products via dermal absorption.
2018); b) Human Early Life Exposome
(HELIX), a pooled sample from four cohorts (total N = 525) (Vrijheid et al.
Il s'agit d'une des premieres etudes sur le sujet a prendre en compte l'exposition globale a tout une serie de polluants (l'"exposome
"), et pas seulement substance par substance, soulignent les auteurs de l'article, publie dans la revue medicale britannique The Lancet Planetary Health.
Believing the genome was incomplete for understanding diseases, Wild (2005) introduced the exposome
as a necessary complement.
Summary: TEHRAN (FNA)- Scientists have measured the human 'exposome
,' or the particulates, chemicals and microbes that individually swaddle us all, in unprecedented detail.
Hoagwood highlighted the importance of work on the exposome
, which the NIMH has described as a new approach to understanding the mechanisms by which environmental factors alter brain and behavior--starting from prenatal development.
Toward capturing the exposome
: Exposure biomarker variability and coexposure patterns in the shared environment.
They are based on the relevant concept that each individual is the result of the sophisticated interplay between environmental factors and its genome, trascriptome, proteome, metabolome, microbiome, epigenome, and exposome
. Thus, it is necessary to perform a more complex combination of investigations based on genetic, transcriptomic, proteomic, metabolomic, microbiomic, and epigenetic evaluations, for obtaining interesting data in the study of these diseases.
To help characterize the temporal nature of developmental adaptations, a panomic approach (i.e., full -omics spectrum of technologies) may be necessary (96) to track molecular events as they arise in response to the maternal exposome