The consortium will investigate which factors of the
exposome are important for health and how these factors work.
B vitamins and pollution, an interesting, emerging, yet incomplete picture of folate and the
exposome. Proc Natl Acad Sci USA 2017;114(20):E3878-E3879.
This article seeks to provide an integrated understanding of the totality of
exposome factors in human health by focusing on the contributions of personal care products via dermal absorption.
2018); b) Human Early Life
Exposome (HELIX), a pooled sample from four cohorts (total N = 525) (Vrijheid et al.
Il s'agit d'une des premieres etudes sur le sujet a prendre en compte l'exposition globale a tout une serie de polluants (l'"
exposome"), et pas seulement substance par substance, soulignent les auteurs de l'article, publie dans la revue medicale britannique The Lancet Planetary Health.
Believing the genome was incomplete for understanding diseases, Wild (2005) introduced the
exposome as a necessary complement.
Summary: TEHRAN (FNA)- Scientists have measured the human '
exposome,' or the particulates, chemicals and microbes that individually swaddle us all, in unprecedented detail.
Hoagwood highlighted the importance of work on the
exposome, which the NIMH has described as a new approach to understanding the mechanisms by which environmental factors alter brain and behavior--starting from prenatal development.
Toward capturing the
exposome: Exposure biomarker variability and coexposure patterns in the shared environment.
They are based on the relevant concept that each individual is the result of the sophisticated interplay between environmental factors and its genome, trascriptome, proteome, metabolome, microbiome, epigenome, and
exposome. Thus, it is necessary to perform a more complex combination of investigations based on genetic, transcriptomic, proteomic, metabolomic, microbiomic, and epigenetic evaluations, for obtaining interesting data in the study of these diseases.
To help characterize the temporal nature of developmental adaptations, a panomic approach (i.e., full -omics spectrum of technologies) may be necessary (96) to track molecular events as they arise in response to the maternal
exposome (Fig.