beta-lactamase

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be·ta-lac·ta·mase

 (bā′tə-lăk′tə-mās′, -māz′, bē′-)
n.
Any of various enzymes that hydrolyze and inactivate beta-lactam antibiotics such as penicillin, found in many antibiotic-resistant bacteria.

[beta-lactam, cyclic amide occurring in penicillins (beta + lact(one) + am(ide)) + -ase.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.beta-lactamase - enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
Translations

be·ta-lac·ta·mase

a. beta-lactamasa, enzima que destruye el conjunto de beta-lactam antibióticos penicílicos haciéndolos no efectivos;
beta-lactamase resistanceresistencia de beta-lactamasa, a algunos tipos de penicilina.
References in periodicals archive ?
The NDA is supported by data from both the EPIC and CARE clinical trials which evaluated the safety and efficacy of plazomicin in patients with serious infections caused by gram-negative pathogens, including extended-spectrum beta-lactamase (ESBL) producing and carbapenem-resistant Enterobacteriaceae (CRE).
Molecular characterization of extended-spectrum beta-lactamase producing Enterobacteriaceae in a Saudi Arabian tertiary hospital.
Phenotypic detection of extended-spectrum beta-lactamase production in Enterobacteriaceae: review and bench guide.
CTX-M-3 extended-spectrum beta-lactamase in a Shigella sonnei clinical isolate: first report from Turkey.
The emergence of a novel ceftazidime-resistant CTX-M extended-spectrum beta-lactamase, CTX-M-55, in both community-onset and hospital-acquired infections in Thailand.
Plasmid-mediated TEM-3 extended-spectrum beta-lactamase production in Salmonella typhimurium in Casablanca.
Toniolo, "Pseudomonas aeruginosa bloodstream infections: risk factors and treatment outcome related to expression of the PER-I extended-spectrum beta-lactamase," BMC Infectious Diseases, vol.
Most of the available data discusses extended-spectrum beta-lactamase (ESBL)-producing E.
Variations in the prevalence of strains expressing an extended-spectrum beta-lactamase phenotype and characterization of isolates from Europe, the Americas, and the Western Pacific region.
Kronman, adding that while it's known that prior exposure to antibiotics is a key risk factor for colonization and development of an infection in adults, similar data among children with respect to ampC and extended-spectrum beta-lactamase (ESBL) are conflicting.
High prevalence of CTX-M-type beta-lactamase in Escherichia coli isolates producing extended-spectrum beta-lactamase (ESBL) and displaying antibiotic co-resistance.

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