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Relating to or involving neural pathways situated outside or independent of the pyramidal tracts.


(ˌɛkstrəpɪrəˌmɪdəl; ˌɛkstrəpɪˈræmɪdəl)
outside the pyramidal tract


(ˌɛk strə pɪˈræm ɪ dl)

1. pertaining to nerve tracts other than the pyramidal tracts, esp. the corpora striata and their associated structures.
2. located outside the pyramidal tracts.
References in periodicals archive ?
Importantly, the rates of akathisia, restlessness and extrapyramidal symptoms combined were less than 1% and similar to placebo in both studies.
Common adverse events reported in the pivotal trials were nausea, akathisia, restlessness, and extrapyramidal symptoms.
Of these, 229 (1.2%) were diagnosed with extrapyramidal syndrome at some point.
Bell's recommendation of this old and forgotten medication and will use it at a low dose, as he suggests, to prevent the extrapyramidal side effects.
Dr.Eyal BallanandEyal Barad, co-founders of Cannabics, believe that the company's clinical experience and personalization platform may allow for personalized cannabinoid solutions for conditions and syndromes such as Alcohol Withdrawal Syndrome (AWS), REM related sleep disorder (RBD),Psychogenic non-epileptic seizures (PNES) and Drug-induced tremors, found as extrapyramidal side effects(EPSE).
When it is necessary the introduce antipsychotics, professionals should avoid classical antipsychotics such as haloperidol due to increased risk of extrapyramidal side-effects causing worsening of motor symptoms [18].
Extrapyramidal symptoms (EPS) are the major constraint in the use of antipsychotic agents.
In order to avoid the development of adverse effects related to extrapyramidal symptoms, approximately 20% of receptors need to be free.
Affected patients have slowly progressive deterioration with cerebellar ataxia, mild or moderate mental retardation, and extrapyramidal and pyramidal symptoms, and seizures and variable macrocephaly (2).
The most common treatment-emergent adverse events observed in the clinical trial were application site reaction, headache and extrapyramidal disorder.
The neurologist initiated carbidopa-levodopa 25mg-100mg three times daily for symptomatic treatment of extrapyramidal features.
Additional signs include behavioral dysfunction, dysphasia, pyramidal or extrapyramidal signs, cortical blindness, and primitive reflexes [3].