Nonalcoholic fatty liver disease (NAFLD) (sin: Liver steatosis, Hepatic steatosis, Fatty infiltration
of the liver, Fatty liver) is an independent disease or a syndrome caused by a fatty infiltration
of hepatic cells.
Liver biopsies were performed percutaneously under ultrasound guidance, or laparoscopically during cholecystectomy for patients with ultrasonographic evidence of steatosis, on patients older than 45 years with fatty infiltration
on ultrasound and/or who had persistently abnormal liver function and/or hepatomegaly.
RV dilation was observed along with extensive replacement type fibrosis and fatty infiltration
. Surviving myocytes entrapped within fibrous and fatty tissue showed degenerative changes and abnormal nuclei.
Diagnosis of non-alcoholic fatty liver disease: The diagnosis of NAFLD requires evidence of fatty infiltration
of the liver in the absence of excessive alcohol consumption and of other secondary causes of chronic liver disease.
Ultrasound is the least informative imaging method; however, fatty infiltration
does cause the liver to light up on ultrasound and the attenuation can be compared with the spleen, Dr.
* Diffuse focal and overall fatty infiltration
, (24) with focal fatty sparing (ie, a spherical hypoechoic area in an otherwise echogenic liver) and poor visualization of the portal and hepatic veins.
raised a concern regarding the ultrasound (US) measurements used in our study, the sensitivity of early fatty infiltration
(<33%), and the limited ability, as we also discussed in our article, to differentiate simple steatosis from inflammation or fibrosis (4).
(35) Fatty infiltration
of muscle also occurs and is linked to insulin resistance at the level of skeletal muscle.
Sowers proposed that metabolic disorders and obesity may affect leg strength by altering glycation products in the muscles, by allowing fatty infiltration
of muscle tissue and compromising selective muscle fibers, or by causing innervation problems.
Some patients in the medical treatment group were told that surgery was not an option because liver biopsy findings showed fatty infiltration
. That was not true.
More rarely, hepatic fatty infiltration
with hepatomegaly, abnormal results of liver function tests and pathologic evidence of hepatocellular damage can be found.
Increased potential to develop into fat cells--and decreased potential to develop into muscle cells --may be an important explanation for the high rate of fatty infiltration
in muscles of patients with chronic rotator cuff tears, even after rotator cuff surgery.